Reissmann B, Kuck K-H, Metzner A
Abteilung für Kardiologie, Asklepios Klinik St. Georg, Lohmühlenstr. 5, 20099, Hamburg, Deutschland.
Herz. 2017 Jun;42(4):352-356. doi: 10.1007/s00059-017-4567-0.
Atrial fibrillation (AF) is the most common form of cardiac arrhythmia. The aim of therapy in symptomatic patients is the establishment of a stable sinus rhythm (SR). Catheter ablation with isolation of the pulmonary veins is the essential component of all forms of ablation therapy and provides the most effective treatment option. The most frequently used technologies for pulmonary vein isolation (PVI) are radiofrequency current (RFC)-based and cryoballoon (CB)-guided ablation. Irrespective of the simplification of PVI, CB ablation is characterized by a short learning curve and short procedural times and demonstrated non-inferiority with respect to safety and efficacy when directly compared to RFC ablation for the treatment of patients with paroxysmal AF; however, the clinical outcome in patients with persistent AF is often insufficient when performing pulmonary vein isolation (PVI) alone for stabilization of SR. Differentiated RFC ablation is the treatment of choice when performing additional ablation strategies beyond PVI in order to improve clinical results with freedom from arrhythmia recurrence.
心房颤动(AF)是最常见的心律失常形式。有症状患者的治疗目标是建立稳定的窦性心律(SR)。肺静脉隔离的导管消融是所有形式消融治疗的重要组成部分,也是最有效的治疗选择。肺静脉隔离(PVI)最常用的技术是基于射频电流(RFC)和冷冻球囊(CB)引导的消融。无论PVI如何简化,CB消融的特点是学习曲线短、手术时间短,在直接与RFC消融比较治疗阵发性AF患者时,在安全性和有效性方面显示出非劣效性;然而,对于持续性AF患者,单独进行肺静脉隔离(PVI)以稳定SR时,临床结果往往不理想。当在PVI之外进行额外的消融策略以改善无心律失常复发的临床结果时,差异化RFC消融是首选治疗方法。