Kil Yun-Seo, Pham Sally T, Seo Eun Kyoung, Jafari Mahtab
College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 03760, Korea.
Department of Pharmaceutical Sciences, University of California, Irvine, CA, 92697, USA.
Arch Pharm Res. 2017 Jun;40(6):655-675. doi: 10.1007/s12272-017-0892-3. Epub 2017 Apr 24.
Angelica keiskei (Miq.) Koidz. (Umbelliferae) has traditionally been used to treat dysuria, dyschezia, and dysgalactia as well as to restore vitality. Recently, the aerial parts of A. keiskei have been consumed as a health food. Various flavonoids, coumarins, phenolics, acetylenes, sesquiterpene, diterpene, and triterpenes were identified as the constituents of A. keiskei. The crude extracts and pure constituents were proven to inhibit tumor growth and ameliorate inflammation, obesity, diabetics, hypertension, and ulcer. The extract also showed anti-thrombotic, anti-oxidative, anti-hyperlipidemic, anti-viral, and anti-bacterial activities. This valuable herb needs to be further studied and developed not only to treat these human diseases but also to improve human health. Currently A. keiskei is commercialized as a health food and additives in health drinks. This article presents a comprehensive review of A. keiskei and its potential place in the improvement of human health.
明日叶（Angelica keiskei (Miq.) Koidz.，伞形科）传统上用于治疗排尿困难、排便困难和乳汁分泌不足，还具有恢复活力的功效。最近，明日叶的地上部分被用作健康食品。已鉴定出明日叶的成分包括各种黄酮类化合物、香豆素、酚类、乙炔类、倍半萜、二萜和三萜。粗提物和纯成分被证明具有抑制肿瘤生长、改善炎症、肥胖、糖尿病、高血压和溃疡的作用。该提取物还具有抗血栓、抗氧化、抗高血脂、抗病毒和抗菌活性。这种珍贵的草药不仅需要进一步研究和开发用于治疗这些人类疾病，还需要用于改善人类健康。目前，明日叶已作为健康食品和健康饮品添加剂实现商业化。本文对明日叶及其在改善人类健康方面的潜在作用进行了全面综述。
