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大麻:印度的神经疗法还是滥用药物?

Cannabis: A Neurological Remedy or a Drug of Abuse in India.

作者信息

Biswas Pronit, Mishra Pooja, Bose Devasish, Durgbanshi Abhilasha

机构信息

Department of Criminology and Forensic Science, Dr. Harisingh Gour University, Sagar. India.

Department of Chemistry, Dr. Harisingh Gour University, Sagar, India.

出版信息

CNS Neurol Disord Drug Targets. 2017;16(5):576-584. doi: 10.2174/1871527316666170424115008.

DOI:10.2174/1871527316666170424115008
PMID:28440191
Abstract

BACKGROUND

Since ancient times, the use of cannabis as a medicine is well documented due to its potential therapeutic activity while subsequently its use as drug of abuse spread increasingly.

OBJECTIVE

The present review sought to give an insight in the history of medical and recreational use of cannabis in India.

CONCLUSION

Indian use of cannabis dates back to Vedic time, mostly for the ritualistic and religious purposes, as documented in the ancient literature. It was India that introduced the medical use of cannabis to neighboring countries. Nevertheless, in the same India, medical use did not propagate due to religious and social stigma related to the plant itself. The pharmacoactive constituents of cannabis and their therapeutic values in Ayurvetic medicine have been here described together with the adverse effects they can cause with special reference to neurological ones, including withdrawal symptoms. Finally, how cannabis made its route to the Indian society has also been discussed.

摘要

背景

自古以来,大麻因其潜在的治疗活性而被广泛记载用于医学,然而随后其作为滥用药物的使用却日益泛滥。

目的

本综述旨在深入了解印度大麻在医学和娱乐用途方面的历史。

结论

印度对大麻的使用可追溯到吠陀时代,主要用于仪式和宗教目的,这在古代文献中有记载。是印度将大麻的医学用途引入了周边国家。然而,在印度本国,由于与该植物本身相关的宗教和社会污名,医学用途并未得到推广。本文描述了大麻的药理活性成分及其在阿育吠陀医学中的治疗价值,以及它们可能引起的不良反应,特别提及了神经方面的不良反应,包括戒断症状。最后,还讨论了大麻进入印度社会的途径。

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Cannabis: A Neurological Remedy or a Drug of Abuse in India.大麻:印度的神经疗法还是滥用药物?
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The Neuroglial Dialog Between Cannabinoids and Hemichannels.大麻素与半通道之间的神经胶质对话
Front Mol Neurosci. 2018 Mar 20;11:79. doi: 10.3389/fnmol.2018.00079. eCollection 2018.