Datta Shivika, Ramamurthy Praveen C, Anand Uttpal, Singh Simranjeet, Singh Amritpal, Dhanjal Daljeet Singh, Dhaka Vaishali, Kumar Sanjay, Kapoor Dhriti, Nandy Samapika, Kumar Manoj, Koshy Eapen P, Dey Abhijit, Proćków Jarosław, Singh Joginder
Department of Zoology, Doaba College, Jalandhar, Punjab 144001, India.
Interdisciplinary Centre for Water Research (ICWaR), Indian Institute of Sciences, Bangalore 560012, Karnataka, India.
Saudi J Biol Sci. 2021 Dec;28(12):7290-7313. doi: 10.1016/j.sjbs.2021.08.036. Epub 2021 Aug 19.
, widely known as 'Marijuana' poses a dilemma for being a blend of both good and bad medicinal effects. The historical use of for both medicinal and recreational purposes suggests it to be a friendly plant. However, whether the misuse of and the cannabinoids derived from it can hamper normal body physiology is a focus of ongoing research. On the one hand, there is enough evidence to suggest that misuse of marijuana can cause deleterious effects on various organs like the lungs, immune system, cardiovascular system, etc. and also influence fertility and cause teratogenic effects. However, on the other hand, marijuana has been found to offer a magical cure for anorexia, chronic pain, muscle spasticity, nausea, and disturbed sleep. Indeed, most recently, the United Nations has given its verdict in favour of declaring it as a non-dangerous narcotic. This review provides insights into the various health effects of and its specialized metabolites and indicates how wise steps can be taken to promote good use and prevent misuse of the metabolites derived from this plant.
大麻，广为人知的“ Marijuana”，因其兼具好坏两种药用效果而构成了一个难题。大麻在药用和娱乐用途上的历史使用表明它是一种友好的植物。然而，大麻及其衍生的大麻素的滥用是否会妨碍正常身体生理机能是正在进行的研究重点。一方面，有足够的证据表明滥用大麻会对肺部、免疫系统、心血管系统等各种器官造成有害影响，还会影响生育能力并导致致畸作用。然而，另一方面，人们发现大麻对厌食症、慢性疼痛、肌肉痉挛、恶心和睡眠障碍有神奇的治疗效果。事实上，最近联合国已做出有利于大麻的裁决，宣布其为非危险麻醉品。本综述深入探讨了大麻及其特定代谢产物的各种健康影响，并指出如何采取明智的措施来促进大麻代谢产物的合理使用并防止滥用。
