Uzeloto Juliana Souza, Ramos Dionei, C F Freire Ana Paula, G D Christofaro Diego, Mara C Ramos Ercy
Universidade Estadual Paulista (UNESP), Faculdade de Ciências e Tecnologia, São Paulo, SP, Brazil.
Universidade Estadual Paulista (UNESP), Faculdade de Ciências e Tecnologia, São Paulo, SP, Brazil.
Braz J Otorhinolaryngol. 2018 May-Jun;84(3):311-317. doi: 10.1016/j.bjorl.2017.03.006. Epub 2017 Apr 8.
Female smoker's present increased susceptibility to several diseases when compared to the opposite gender. However, there are no studies showing differences in nasal mucociliary transport behavior between male and female smokers.
To compare the nasal mucociliary transportability in male and female smokers and non-smokers, taking into consideration age, anthropometric data, smoking load and pulmonary function.
The analysis included 139 individuals (33 men and 37 women smokers and 32 men and 37 women non-smokers). All participants answered an initial interview to obtain personal data and smoking load. Anthropometric data and carbon monoxide in the exhaled air were assessed. Individuals also performed pulmonary function test and Saccharin Transit Time test. To compare saccharin transit time values between men and women, smokers and non-smokers, stratification of all independent variables was performed (sociodemographic, smoking and respiratory variables) into two categories: below and above the median values.
There was no difference between men and women, smokers and non-smokers, regarding nasal mucociliary transportability. Significant differences were only observed between non-smokers. Among those with less forced vital capacity values (<97.37% of predicted), women presented mucociliary transport faster than men. Moreover, it was observed influence of BMI and COex (women smokers), FCV and FEV1 (men non-smokers) and FEF (women non-smokers) on saccharin transit time values.
Based on the findings of this study, nasal mucociliary transport in male and female adult smokers, apparently healthy, are similar.
与男性相比，女性吸烟者目前对多种疾病的易感性增加。然而，尚无研究表明男性和女性吸烟者的鼻黏液纤毛运输行为存在差异。
比较男性和女性吸烟者及非吸烟者的鼻黏液纤毛运输能力，同时考虑年龄、人体测量数据、吸烟量和肺功能。
分析纳入了139名个体（33名男性吸烟者、37名女性吸烟者、32名男性非吸烟者和37名女性非吸烟者）。所有参与者都接受了初步访谈以获取个人数据和吸烟量。评估了人体测量数据和呼出气体中的一氧化碳含量。个体还进行了肺功能测试和糖精转运时间测试。为了比较男性和女性、吸烟者和非吸烟者之间的糖精转运时间值，对所有自变量（社会人口统计学、吸烟和呼吸变量）进行分层，分为两类：中位数以下和中位数以上。
在鼻黏液纤毛运输能力方面，男性与女性、吸烟者与非吸烟者之间没有差异。仅在非吸烟者之间观察到显著差异。在用力肺活量值较低（<预测值的97.37%）的人群中，女性的黏液纤毛运输速度比男性快。此外，还观察到体重指数和呼出一氧化碳（女性吸烟者）、用力肺活量和第一秒用力呼气量（男性非吸烟者）以及用力呼气流量（女性非吸烟者）对糖精转运时间值的影响。
基于本研究的结果，表面健康的成年男性和女性吸烟者的鼻黏液纤毛运输情况相似。
