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松果体:家麻雀昼夜节律系统中的一个起搏器。

The pineal gland: a pacemaker within the circadian system of the house sparrow.

作者信息

Zimmerman N H, Menaker M

出版信息

Proc Natl Acad Sci U S A. 1979 Feb;76(2):999-1003. doi: 10.1073/pnas.76.2.999.

Abstract

Transplantation of pineal tissue into the anterior chamber of the eye rapidly reestablishes rhythmicity in arhythmic pinealectomized sparrows and also transfers the phase of the donor bird's rhythm to the host. Thus, the transplanted pineal does not merely permit rhythmicity to be expressed but rather transfers an oscillation that controls the remainder of the circadian system and restores the capacity for self-sustained rhythmicity. Long-term recordings, during which sparrosw were exposed to various lighting conditions, demonstrate a remarkable similarity between the circadian system in normal birds and that in birds bearing pineal transplants.

摘要

将松果体组织移植到眼的前房能迅速恢复已摘除松果体而失去节律的麻雀的节律性,并且还能将供体鸟的节律相位传递给宿主。因此,移植的松果体不仅允许节律性得以表达,而且还传递一种振荡,这种振荡控制着昼夜节律系统的其余部分,并恢复自我维持节律性的能力。在让麻雀暴露于各种光照条件下的长期记录过程中,显示出正常鸟类的昼夜节律系统与接受松果体移植的鸟类的昼夜节律系统之间存在显著相似性。

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本文引用的文献

1
Pineal function: the biological clock in the sparrow?松果体功能:麻雀体内的生物钟?
Science. 1968 Jun 7;160(3832):1125-7. doi: 10.1126/science.160.3832.1125.
3
Reproductive effects of the mammalian pineal.
Am Zool. 1970 May;10(2):247-58. doi: 10.1093/icb/10.2.247.
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Endocrinology. 1975 Apr;96(4):848-53. doi: 10.1210/endo-96-4-848.
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Biol Reprod. 1976 Aug;15(1):94-7. doi: 10.1095/biolreprod15.1.94.
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Timekeeping by the pineal gland.
Science. 1977 Sep 16;197(4309):1181-3. doi: 10.1126/science.897660.

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