Aref Ahmad A, Gedde Steven J, Budenz Donald L
Dev Ophthalmol. 2017;59:43-52. doi: 10.1159/000458485. Epub 2017 Apr 25.
Glaucoma drainage implant (GDI) surgery represents a significant advance in the treatment of refractory glaucomas. Recent randomized clinical trials have compared the efficacy and safety of this technique to standard trabeculectomy. Several types of implant are currently available and differ in surface area, shape, composition, and the presence or absence of a flow-restricting valve. Two separate prospective, randomized clinical trials comparing 2 types of GDI have reported results after 5 years of follow-up. GDIs may be placed in the anterior chamber, ciliary sulcus, or pars plana. Several types of patch graft material may be utilized to prevent tube erosion. Potential complications of GDI surgery may relate to immediate or late-onset hypotony, motility disturbances, corneal decompensation, or tube erosion.
青光眼引流植入物（GDI）手术是难治性青光眼治疗的一项重大进展。近期的随机临床试验已将该技术的疗效和安全性与标准小梁切除术进行了比较。目前有几种类型的植入物，它们在表面积、形状、成分以及是否存在限流阀方面存在差异。两项比较两种GDI的独立前瞻性随机临床试验报告了5年随访后的结果。GDI可置于前房、睫状沟或睫状体扁平部。可使用几种类型的补片移植材料来防止引流管侵蚀。GDI手术的潜在并发症可能与即刻或迟发性低眼压、眼球运动障碍、角膜失代偿或引流管侵蚀有关。
