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外阴部乳房外佩吉特病:一种罕见疾病。

Extramammary Paget's disease of vulva: A rare entity.

作者信息

Yadav Sandhya, Gahalaut Pratik, Soodan Hardev Singh, Mishra Nitin, Rastogi Madhur Kant

机构信息

Department of Dermatology, Shri Ram Murti Smarak Institute of Medical Sciences, Bhojipura, Bareilly, Uttar Pradesh, India.

出版信息

Indian J Sex Transm Dis AIDS. 2017 Jan-Jun;38(1):76-77. doi: 10.4103/0253-7184.196891.

DOI:10.4103/0253-7184.196891
PMID:28442808
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5389220/
Abstract

Extramammary Paget's disease is a rare cutaneous, intraepithelial adenocarcinoma involving primarily the epidermis but occasionally extending into the underlying dermis. The condition typically presents as a red, velvety, pruritic skin rash of the vulva region which closely mimics a multitude of other, more common conditions. As a result, vulvar Paget's disease is frequently misdiagnosed, leading to an often lengthy lag time (an average of about 2-3 years) between the onset of symptoms and diagnosis.

摘要

乳房外佩吉特病是一种罕见的皮肤原位腺癌,主要累及表皮,但偶尔也会延伸至下方的真皮层。该病通常表现为外阴区域红色、天鹅绒样、瘙痒性皮疹,与许多其他更常见的病症极为相似。因此,外阴佩吉特病常被误诊,导致症状出现与诊断之间往往有较长的延迟时间(平均约2至3年)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/839b/5389220/58840e2a306a/IJSTD-38-76-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/839b/5389220/1e8611e333b3/IJSTD-38-76-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/839b/5389220/58840e2a306a/IJSTD-38-76-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/839b/5389220/1e8611e333b3/IJSTD-38-76-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/839b/5389220/58840e2a306a/IJSTD-38-76-g002.jpg

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A Clinicopathological and Immunohistochemical Profile of Primary Extra Mammary Paget's Disease in Skin of Colour: A Case Series.有色人种皮肤原发性乳房外佩吉特病的临床病理及免疫组化特征:病例系列
Indian J Dermatol. 2023 Jul-Aug;68(4):488. doi: 10.4103/ijd.ijd_99_23.
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An unusual secondary extramammary Paget's disease of vulva.一例罕见的外阴部继发性乳房外佩吉特病。
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本文引用的文献

1
Extramammary Paget's disease with the appearance of a nodule: a case report.结节状外观的乳房外帕哲病:一例报告。
BMC Cancer. 2010 Aug 4;10:405. doi: 10.1186/1471-2407-10-405.
2
Extramammary Paget's disease of the penis: a case report and review of the literature.阴茎外佩吉特病:一例病例报告及文献综述
J Med Case Rep. 2009 Jan 6;3:4. doi: 10.1186/1752-1947-3-4.
3
Mammary and extramammary Paget's disease.乳腺及乳腺外佩吉特病。
J Clin Pathol. 2000 Oct;53(10):742-9. doi: 10.1136/jcp.53.10.742.
4
Paget's disease of the vulva: pathology, pattern of involvement, and prognosis.外阴佩吉特病:病理学、受累模式及预后
Gynecol Oncol. 2000 Apr;77(1):183-9. doi: 10.1006/gyno.2000.5741.
5
The Roswell Park Cancer Institute experience with extramammary Paget's disease.罗斯韦尔帕克癌症研究所关于乳房外佩吉特病的经验。
Br J Dermatol. 2000 Jan;142(1):59-65. doi: 10.1046/j.1365-2133.2000.03242.x.
6
Extramammary Paget's disease of the vulva: report of five cases and review of the literature.外阴部乳房外佩吉特病:5例报告并文献复习
Eur J Gynaecol Oncol. 1999;20(2):98-101.