新生仔猪轮状病毒和肠道病毒的单一及混合感染：临床症状和微观病变

Janke B H, Morehouse L G, Solorzano R F

Department of Veterinary Pathology, College of Veterinary Medicine, University of Missouri, Columbia 65211.

Can J Vet Res. 1988 Jul;52(3):364-9.

Neonatal colostrum-deprived pigs were inoculated with cell-culture preparations of three rotaviruses and three enteroviruses, singly or in combination. The three enteroviruses established intestinal and systemic infection but did not induce diarrhea or intestinal lesions. The three rotaviruses produced severe enteric disease characterized by profuse watery diarrhea, dehydration and death. Villi were severely stunted. All three isolates were equally virulent. Inoculation with three different rotavirus-enterovirus combinations resulted in disease less severe than that produced by the rotaviruses alone. Intestinal lesions were less extensive and fewer pigs became moribund or died.

将新生期未摄入初乳的仔猪单独或联合接种三种轮状病毒和三种肠道病毒的细胞培养制剂。三种肠道病毒引发了肠道和全身感染，但未导致腹泻或肠道病变。三种轮状病毒引发了严重的肠道疾病，其特征为大量水样腹泻、脱水和死亡。肠绒毛严重发育不良。所有三种分离株的毒力相同。接种三种不同的轮状病毒 - 肠道病毒组合所导致的疾病比单独接种轮状病毒所引发的疾病症状要轻。肠道病变范围更小，濒死或死亡的仔猪数量更少。