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人类视黄酸受体定位于17号染色体的q21带。

Mapping of the human retinoic acid receptor to the q21 band of chromosome 17.

作者信息

Mattei M G, Petkovich M, Mattei J F, Brand N, Chambon P

机构信息

U.242 INSERM, Hôpital d'Enfants de la Timone, Marseille, France.

出版信息

Hum Genet. 1988 Oct;80(2):186-8. doi: 10.1007/BF00702866.

DOI:10.1007/BF00702866
PMID:2844649
Abstract

Recombinant plasmid containing cDNA insert from the human retinoic acid receptor was radiolabeled and hybridized in situ to metaphase chromosome preparations. The results localized the human retinoic acid receptor to the q21 band of chromosome 17.

摘要

将含有来自人视黄酸受体的cDNA插入片段的重组质粒进行放射性标记，并原位杂交到中期染色体标本上。结果将人视黄酸受体定位于17号染色体的q21带。

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Mapping of the human retinoic acid receptor to the q21 band of chromosome 17.人类视黄酸受体定位于17号染色体的q21带。
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本文引用的文献

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A human c-erbA oncogene homologue is closely proximal to the chromosome 17 breakpoint in acute promyelocytic leukemia.一种人类c-erbA癌基因同源物紧邻急性早幼粒细胞白血病中17号染色体的断点。
Proc Natl Acad Sci U S A. 1984 Jul;81(14):4495-9. doi: 10.1073/pnas.81.14.4495.
2
Chromosomal localisation of the human homologues to the oncogenes erbA and B.人类原癌基因erbA和B同源物的染色体定位
EMBO J. 1984 Jan;3(1):159-63. doi: 10.1002/j.1460-2075.1984.tb01777.x.
3
DNA probe localization at 18p113 band by in situ hybridization and identification of a small supernumerary chromosome.
追求科学卓越是促进还是阻碍转化医学研究：来自血液系统恶性肿瘤的历史视角。
Blood Cancer J. 2022 Oct 7;12(10):142. doi: 10.1038/s41408-022-00738-x.
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History of Acute Promyelocytic Leukemia.急性早幼粒细胞白血病病史。
Clin Hematol Int. 2021 Jul 19;3(4):142-152. doi: 10.2991/chi.k.210703.001. eCollection 2021 Dec.
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Next-generation assessment of human epidermal growth factor receptor 2 gene (ERBB2) amplification status in invasive breast carcinoma: a focus on Group 4 by use of the 2018 American Society of Clinical Oncology/College of American Pathologists HER2 testing guideline.下一代人表皮生长因子受体 2 基因（ERBB2）在浸润性乳腺癌中扩增状态的评估：重点关注 2018 年美国临床肿瘤学会/美国病理学家学院 HER2 检测指南的第 4 组。
Histopathology. 2021 Mar;78(4):498-507. doi: 10.1111/his.14241. Epub 2020 Oct 12.
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Acute Promyelocytic Leukemia: A History over 60 Years-From the Most Malignant to the most Curable Form of Acute Leukemia.急性早幼粒细胞白血病：60 多年的历程——从最恶性的急性白血病形式到最可治愈的形式
Oncol Ther. 2019 Jun;7(1):33-65. doi: 10.1007/s40487-018-0091-5. Epub 2019 Feb 5.
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RARG Gene Dysregulation in Acute Myeloid Leukemia.急性髓系白血病中的视黄酸受体γ基因失调
Front Mol Biosci. 2019 Oct 24;6:114. doi: 10.3389/fmolb.2019.00114. eCollection 2019.
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Nucl Receptor Res. 2015 Dec;2. doi: 10.11131/2015/101182. Epub 2015 Dec 15.
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通过原位杂交将DNA探针定位在18p11.3带，并鉴定出一条小的额外染色体。
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