Goodwin Anthony, Matthews Nicole L, Smith Christopher J
Southwest Autism Research and Resource Center, 300 North 18th Street, Phoenix, AZ, 85006, USA.
J Autism Dev Disord. 2017 Jul;47(7):2176-2188. doi: 10.1007/s10803-017-3133-1.
Research suggests that toddlers with no language delay (NLD) should have better outcomes than those with language delay (LD). However, the predictive utility of language milestones relative to co-varying factors such as age at diagnosis, IQ, and ASD symptomatology is unclear. This study compared school-aged children with ASD and NLD (n = 59) to a well-matched group with ASD and LD (n = 59). The LD group was diagnosed at younger ages and their historical ASD symptoms were more severe than the NLD group. The groups were similar in current ASD symptoms and adaptive functioning at school age. Language milestones were correlated with adaptive functioning, but IQ and social symptoms of ASD were stronger predictors of functioning at school age. Therefore, language milestones may not be the best indicators of prognosis for children who are diagnosed after toddlerhood.
研究表明，没有语言发育迟缓（NLD）的幼儿应该比有语言发育迟缓（LD）的幼儿有更好的结果。然而，相对于诸如诊断年龄、智商和自闭症症状等共同变化因素，语言里程碑的预测效用尚不清楚。本研究将患有自闭症和无语言发育迟缓（NLD）的学龄儿童（n = 59）与一组匹配良好的患有自闭症和语言发育迟缓（LD）的儿童（n = 59）进行了比较。语言发育迟缓（LD）组在较小年龄被诊断，且其既往自闭症症状比无语言发育迟缓（NLD）组更严重。两组在当前自闭症症状和学龄期适应性功能方面相似。语言里程碑与适应性功能相关，但智商和自闭症的社交症状是学龄期功能更强的预测因素。因此，对于幼儿期后被诊断的儿童，语言里程碑可能不是预后的最佳指标。
