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An analytical reconstruction model of the spread-out Bragg peak using laser-accelerated proton beams.

作者信息

Tao Li, Zhu Kun, Zhu Jungao, Xu Xiaohan, Lin Chen, Ma Wenjun, Lu Haiyang, Zhao Yanying, Lu Yuanrong, Chen Jia-Er, Yan Xueqing

机构信息

State Key Laboratory of Nuclear Physics and Technology, Peking University, Beijing 100871, People's Republic of China.

出版信息

Phys Med Biol. 2017 Jul 7;62(13):5200-5212. doi: 10.1088/1361-6560/aa6fce. Epub 2017 Apr 27.

Abstract

With the development of laser technology, laser-driven proton acceleration provides a new method for proton tumor therapy. However, it has not been applied in practice because of the wide and decreasing energy spectrum of laser-accelerated proton beams. In this paper, we propose an analytical model to reconstruct the spread-out Bragg peak (SOBP) using laser-accelerated proton beams. Firstly, we present a modified weighting formula for protons of different energies. Secondly, a theoretical model for the reconstruction of SOBPs with laser-accelerated proton beams has been built. It can quickly calculate the number of laser shots needed for each energy interval of the laser-accelerated protons. Finally, we show the 2D reconstruction results of SOBPs for laser-accelerated proton beams and the ideal situation. The final results show that our analytical model can give an SOBP reconstruction scheme that can be used for actual tumor therapy.

摘要

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