特定人群中的小儿葡萄膜炎：免疫抑制治疗可改善预后。
Pediatric Uveitis in a Well-Defined Population: Improved Outcomes with Immunosuppressive Therapy.
机构信息
a Department of Ophthalmology , Royal Victoria Hospital , Belfast, UK.
b Centre for Experimental Medicine, Queens University of Belfast, Belfast, UK.
出版信息
Ocul Immunol Inflamm. 2018;26(6):978-985. doi: 10.1080/09273948.2017.1305420. Epub 2017 Apr 27.
PURPOSE
The aim of this study is to assess the incidence, etiology, visual outcomes, and complication rates of pediatric uveitis patients at a dedicated multidisciplinary uveitis clinic in Northern Ireland.
METHODS
Data were collected from charts of all patients attending the clinic at the Belfast Health and Social Care Trust between 2011 and 2015. Demographics, disease characteristics, treatments, visual acuity, and complications were recorded.
RESULTS
There were 94 patients with uveitis onset before the age of 16 years. Etiology was mixed with JIAU the leading cause accounting for 48% of patients. Thirty-seven percent of patients had known complications at presentation and 65% by final visit. Systemic treatments were used in 65% of cases. Ninety-two percent of eyes had a final visual acuity ≥ 6/12 at a mean follow-up of 5 years.
CONCLUSIONS
The etiology of uveitis in this pediatric population is mixed. With close monitoring, most patients maintain good vision.
目的
本研究旨在评估北爱尔兰一家专门的多学科葡萄膜炎诊所中儿科葡萄膜炎患者的发病率、病因、视力结果和并发症发生率。
方法
收集 2011 年至 2015 年期间在贝尔法斯特健康和社会保健信托基金会就诊的所有患者的病历数据。记录人口统计学、疾病特征、治疗、视力和并发症。
结果
有 94 名患者在 16 岁之前出现葡萄膜炎。病因复杂，幼年特发性关节炎（JIAU）是主要病因，占患者的 48%。37%的患者在就诊时就有已知的并发症，65%的患者在最后一次就诊时有并发症。65%的病例使用了全身治疗。92%的眼在平均 5 年的随访中有最终视力≥6/12。
结论
该儿科人群葡萄膜炎的病因复杂。通过密切监测，大多数患者保持良好的视力。
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