a Department of Ophthalmology , Croix-Rousse University Hospital , Lyon , France.
Ocul Immunol Inflamm. 2018;26(4):612-613. doi: 10.1080/09273948.2017.1306086. Epub 2017 Apr 27.
In response to the article by Parodi et al. about choroidal neovascularization (CNV) associated with Multiple Evanescent White Dot Syndrome (MEWDS) treated with intravitreal Ranibizumab. This article highlights the efficacy of intravitreal Ranibizumab in the treatment of CNV associated with MEWDS. In our experience, CNV is mostly associated with MEWDS in cases of a wider inflammatory spectrum such as overlapping syndrome with multifocal choroiditis (MFC) or punctuate inner choroidopathy (PIC). The whole pattern of the case presented in the article is compatible with the diagnosis of PIC, meaning that this case described an overlapping between MEWDS and PIC diagnoses. Although the authors wrote that CNV is secondary to MEWDS, another possible hypothesis is that CNV is secondary to PIC. Thus, MEWDS could be secondary to PIC and/or CNV.
针对 Parodi 等人关于与多发性一过性白点综合征(MEWDS)相关的脉络膜新生血管(CNV)接受玻璃体内雷珠单抗治疗的文章。本文强调了玻璃体内雷珠单抗治疗与 MEWDS 相关的 CNV 的疗效。根据我们的经验,在炎症谱较宽的情况下,如与多灶性脉络膜炎(MFC)或点状内层脉络膜病变(PIC)重叠的综合征,CNV 主要与 MEWDS 相关。本文所描述病例的整体模式与 PIC 的诊断相符,这意味着该病例描述了 MEWDS 和 PIC 诊断之间的重叠。尽管作者写道 CNV 继发于 MEWDS,但另一种可能的假设是 CNV 继发于 PIC。因此,MEWDS 可能继发于 PIC 和/或 CNV。