Eye Center, Renmin Hospital of Wuhan University, Wuhan University, Wuhan, China.
Department of Ocular Fundus Disease, Wuhan EyeGood Ophthalmic Hospital, Wuhan, China; and.
Retina. 2023 Jul 1;43(7):1122-1131. doi: 10.1097/IAE.0000000000003776.
To present and compare the clinical features and multimodal imaging (MMI) findings of the primary form of multiple evanescent white dot syndrome (MEWDS) and MEWDS secondary to multifocal choroiditis/punctate inner choroidopathy (MFC/PIC).
A prospective case series. Thirty eyes of 30 MEWDS patients were included and divided into the primary MEWDS group and MEWDS secondary to MFC/PIC group. Demographic, epidemiologic, and clinical characteristics and MEWDS-related MMI findings of the two groups were compared.
Seventeen eyes from 17 patients with primary MEWDS and 13 eyes from 13 patients with MEWDS secondary to MFC/PIC were evaluated. Patients with MEWDS secondary to MFC/PIC tended to have a higher degree of myopia than those with primary MEWDS. No other significant differences in demographic, epidemiologic, and clinical characteristics and MMI findings were found between the two groups.
"MEWDS-like reaction" hypothesis seems to be correct for MEWDS secondary to MFC/PIC, and the authors highlight the importance of MMI examinations in MEWDS. Further research is needed to confirm whether the hypothesis is applicable to other forms of secondary MEWDS.
介绍和比较多发性一过性白点综合征（MEWDS）原发性和多灶性脉络膜炎/点状内层脉络膜炎（MFC/PIC）继发 MEWDS 的临床特征和多模态影像学（MMI）表现。
前瞻性病例系列研究。纳入 30 例 MEWDS 患者的 30 只眼，分为原发性 MEWDS 组和 MFC/PIC 继发 MEWDS 组。比较两组的人口统计学、流行病学、临床特征和与 MEWDS 相关的 MMI 发现。
评估了 17 例原发性 MEWDS 患者的 17 只眼和 13 例 MFC/PIC 继发 MEWDS 患者的 13 只眼。MFC/PIC 继发 MEWDS 患者的近视程度高于原发性 MEWDS 患者。两组在人口统计学、流行病学和临床特征以及 MMI 发现方面无其他显著差异。
对于 MFC/PIC 继发 MEWDS，“MEWDS 样反应”假说似乎是正确的，作者强调了 MMI 检查在 MEWDS 中的重要性。需要进一步的研究来证实该假说是否适用于其他形式的继发 MEWDS。
