2016年8月至2017年1月期间，意大利发生3例携带mcr-1基因的耐黏菌素大肠杆菌血流感染病例。
Three cases of mcr-1-positive colistin-resistant Escherichia coli bloodstream infections in Italy, August 2016 to January 2017.
作者信息
Corbella Marta, Mariani Bianca, Ferrari Carolina, Comandatore Francesco, Scaltriti Erika, Marone Piero, Cambieri Patrizia
机构信息
SC Microbiologia e Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
These authors contributed equally to this work.
出版信息
Euro Surveill. 2017 Apr 20;22(16). doi: 10.2807/1560-7917.ES.2017.22.16.30517.
Abstract
We describe three cases of bloodstream infection caused by colistin-resistant Escherichia coli in patients in a tertiary hospital in Italy, between August 2016 and January 2017. Whole genome sequencing detected the mcr-1 gene in three isolated strains belonging to different sequence types (STs). This occurrence of three cases with mcr-1-positive E. coli belonging to different STs in six months suggests a widespread problem in settings where high multidrug resistance is endemic such as in Italy.
摘要
我们描述了2016年8月至2017年1月期间，意大利一家三级医院中3例由耐黏菌素大肠杆菌引起的血流感染病例。全基因组测序在3株属于不同序列类型（STs）的分离菌株中检测到mcr-1基因。6个月内出现3例属于不同STs的mcr-1阳性大肠杆菌病例，这表明在意大利等多药耐药高发的地区存在一个普遍问题。
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