Parikh P M, Charak B S, Banavali S D, Advani S H, Saikia T K, Gopal R, Borges A M, Chinoy R F, Desai P B
Department of Medical Oncology, Tata Memorial Hospital, Bombay, India.
J Surg Oncol. 1988 Oct;39(2):126-8. doi: 10.1002/jso.2930390212.
Fifteen cases of histologically proven Askin Rosai tumor were treated at Tata Memorial Hospital over a period of 3 years. Patients included 12 men and three women. Clinical features included chest wall mass (14), pain (11), bony involvement (6), fever (4), dyspnoea (4), weight loss (1), cough (1), and hemoptysis (1). Previously treated patients received different treatment protocols, which made evaluation difficult. Of our ten patients who have completed induction therapy, five received vincristine and cyclophosphamide, whereas the other five received more aggressive chemotherapy. Complete remission has been achieved in two and four of these patients, respectively. One patient in each group had recurrence of the disease, in both cases at the local site. Thus, from our preliminary data, we suggest that Askin Rosai tumor should be treated with complete surgical excision followed by an aggressive combination of chemotherapy and local radiotherapy.
在三年时间里，塔塔纪念医院收治了15例经组织学证实的阿斯金罗萨伊肿瘤患者。患者包括12名男性和3名女性。临床特征包括胸壁肿块（14例）、疼痛（11例）、骨质受累（6例）、发热（4例）、呼吸困难（4例）、体重减轻（1例）、咳嗽（1例）和咯血（1例）。先前接受治疗的患者采用了不同的治疗方案，这使得评估变得困难。在我们完成诱导治疗的10名患者中，5名接受了长春新碱和环磷酰胺治疗，而另外5名接受了更积极的化疗。这些患者中分别有2名和4名实现了完全缓解。每组各有1名患者疾病复发，均为局部复发。因此，根据我们的初步数据，我们建议阿斯金罗萨伊肿瘤应采用完整的手术切除，随后进行积极的化疗和局部放疗联合治疗。
