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标准生命体征对预测通过直升机转运的钝性创伤患者的死亡率及院前救生干预需求的无效性:对新措施的再次呼吁。

Inefficacy of standard vital signs for predicting mortality and the need for prehospital life-saving interventions in blunt trauma patients transported via helicopter: A repeated call for new measures.

作者信息

Liu Nehemiah T, Holcomb John B, Wade Charles E, Salinas Jose

机构信息

From the U.S. Army Institute of Surgical Research (N.T.L., J.S.), Fort Sam Houston; and Center for Translational Injury Research, Department of Surgery (J.B.H., C.E.W.), University of Texas Health Science Center at Houston, Houston, Texas.

出版信息

J Trauma Acute Care Surg. 2017 Jul;83(1 Suppl 1):S98-S103. doi: 10.1097/TA.0000000000001482.

Abstract

BACKGROUND

The aim of this study was to investigate the efficacy of traditional vital signs for predicting mortality and the need for prehospital lifesaving interventions (LSIs) in blunt trauma patients requiring helicopter transport to a Level I trauma center. Our hypothesis was that standard vital signs are not sufficient for identifying or determining treatment for those patients most at risk.

METHODS

This study involved prehospital trauma patients suffering from blunt trauma (motor vehicle/cycle collision) and transported from the point of injury via helicopter. Means and standard deviations for vital signs and Glasgow Coma Scale (GCS) scores were obtained for non-LSI versus LSI and survivor versus nonsurvivor patient groups and then compared using Wilcoxon statistical tests. Variables with statistically significant differences between patient groups were then used to develop multivariate logistic regression models for predicting mortality and/or the need for prehospital LSIs. Receiver-operating characteristic (ROC) curves were also obtained to compare these models.

RESULTS

A final cohort of 195 patients was included in the analysis. Thirty (15%) patients received a total of 39 prehospital LSIs. Of these, 12 (40%) died. In total, 33 (17%) patients died. Of these, 21 (74%) did not receive prehospital LSIs. Model variables were field heart rate, lowest systolic blood pressure, shock index, pulse pressure, and GCS components. Using vital signs alone, ROC curves demonstrated poor prediction of LSI needs, mortality, and nonsurvivors who did not receive LSIs (area under the curve [AUC], AUCs: 0.72, 0.65, and 0.61). When using both vital signs and GCS, ROC curves still demonstrated poor prediction of nonsurvivors overall and nonsurvivors who did not receive LSIs (AUCs: 0.67, 0.74).

CONCLUSION

The major implication of this study was that traditional vital signs cannot identify or determine treatment for many prehospital blunt trauma patients who are at great risk. This study reiterated the need for new measures to improve blunt trauma triage and prehospital care.

LEVEL OF EVIDENCE

Therapeutic/care management, level IV.

摘要

背景

本研究的目的是调查传统生命体征对预测钝性创伤患者死亡率以及对需要直升机转运至一级创伤中心的患者进行院前救生干预(LSI)必要性的有效性。我们的假设是,标准生命体征不足以识别或确定那些风险最高患者的治疗方案。

方法

本研究纳入了因钝性创伤(机动车/自行车碰撞)而在院前受伤并通过直升机从受伤地点转运的患者。获取了非LSI组与LSI组以及存活组与非存活组患者的生命体征和格拉斯哥昏迷量表(GCS)评分的均值和标准差,然后使用Wilcoxon统计检验进行比较。然后将患者组之间具有统计学显著差异的变量用于建立预测死亡率和/或院前LSI必要性的多变量逻辑回归模型。还获得了受试者操作特征(ROC)曲线以比较这些模型。

结果

最终共有195例患者纳入分析。30例(15%)患者共接受了39次院前LSI。其中,12例(40%)死亡。总共有33例(17%)患者死亡。其中,21例(74%)未接受院前LSI。模型变量包括现场心率、最低收缩压、休克指数、脉压和GCS各组成部分。仅使用生命体征时,ROC曲线显示对LSI需求、死亡率以及未接受LSI的非存活者的预测效果较差(曲线下面积[AUC],AUC分别为:0.72、0.65和0.61)。当同时使用生命体征和GCS时,ROC曲线对总体非存活者以及未接受LSI的非存活者的预测效果仍然较差(AUC分别为:0.67、0.74)。

结论

本研究的主要意义在于,传统生命体征无法识别或确定许多院前钝性创伤高危患者的治疗方案。本研究重申了需要新的措施来改善钝性创伤分诊和院前护理。

证据水平

治疗/护理管理,四级。

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