Chung C Y, Li S H, Li K K W
Department of Ophthalmology, United Christian Hospital, Kowloon, Hong Kong.
Department of Ophthalmology, Tseung Kwan O Hospital, Kowloon, Hong Kong.
Eye (Lond). 2017 Sep;31(9):1373-1379. doi: 10.1038/eye.2017.71. Epub 2017 Apr 28.
PurposeTo describe and correlate the morphological and clinical features of focal choroidal excavation (FCE).MethodsThis is a consecutive case series from the review of the 4436 optical coherence tomography scans performed by Kowloon East Cluster Ophthalmic Service from 1 August 2014-31 January 2016. Statistical analysis was performed on SPSS 18.0 (SPSS, Chicago, IL, USA). A significance level of P<0.05 was taken.ResultsAll 16 patients with FCE had unilateral involvement. The mean age of diagnosis was 52.56±14.00. The mean greatest linear dimension (GLD) of FCE was 636.25±265.11 μm. The mean choroidal thickness was 183.63±52.39 μm. Fourteen FCEs (87.5%) were conforming and two were non-conforming (12.5%). In the eyes with FCE, concurrent macular pathology was present in four cases (25.0%). Tractional pathologies of macular pucker and macular scar corresponded to the two non-conforming FCEs in the series. Polypoidal choroidal vasculopathy (PCV) and lacquer crack had a close topographic relationship with the FCE. The mean GLD was significantly larger in eyes with concurrent macular pathology than those without (878.00 vs 555.67 μm, P=0.029). In the fellow eyes, concurrent macular pathology was present in 5 cases (31.3%): PCV in 3 cases and chronic central serous chorioretinopathy in 2 cases.ConclusionAs a significant proportion of FCE is associated with concurrent macular pathology in the involved or fellow eye, angiography for both eyes is recommended even for asymptomatic cases. The GLD of FCE may have clinical value in risk stratification.
描述并关联局灶性脉络膜凹陷(FCE)的形态学和临床特征。
这是一项连续病例系列研究,回顾了2014年8月1日至2016年1月31日九龙东联网眼科服务部进行的4436次光学相干断层扫描。使用SPSS 18.0(美国伊利诺伊州芝加哥市SPSS公司)进行统计分析。显著性水平设定为P<0.05。
所有16例FCE患者均为单眼受累。诊断时的平均年龄为52.56±14.00岁。FCE的平均最大线性尺寸(GLD)为636.25±265.11μm。脉络膜平均厚度为183.63±52.39μm。14个FCE(87.5%)符合标准,2个不符合标准(12.5%)。在FCE患眼中,4例(25.0%)同时存在黄斑病变。黄斑皱襞和黄斑瘢痕的牵引性病变与该系列中的2个不符合标准的FCE相对应。息肉样脉络膜血管病变(PCV)和漆裂纹与FCE有密切的地形关系。同时存在黄斑病变的患眼的平均GLD显著大于无黄斑病变的患眼(878.00对555.67μm,P=0.029)。在对侧眼中,5例(31.3%)同时存在黄斑病变:3例为PCV,2例为慢性中心性浆液性脉络膜视网膜病变。
由于相当一部分FCE在患眼或对侧眼中与同时存在的黄斑病变相关,因此即使是无症状病例,也建议对双眼进行血管造影。FCE的GLD在风险分层中可能具有临床价值。