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本文引用的文献

1
Focal choroidal excavation in patients with central serous chorioretinopathy.中心性浆液性脉络膜视网膜病变患者的局灶性脉络膜凹陷
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2
Acquired focal choroidal excavation associated with multiple evanescent white dot syndrome: observations at onset and a pathogenic hypothesis.获得性局限性脉络膜凹陷与多发性一过性白点综合征相关:发病时的观察及致病假说
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3
Association of focal choroidal excavation with age-related macular degeneration.局限性脉络膜凹陷与年龄相关性黄斑变性的关联
Invest Ophthalmol Vis Sci. 2014 Sep 4;55(9):6046-54. doi: 10.1167/iovs.14-14723.
4
Evaluation of focal choroidal excavation in the macula using swept-source optical coherence tomography.应用扫频源光学相干断层扫描评估黄斑区局灶性脉络膜凹陷。
Eye (Lond). 2014 Sep;28(9):1088-94. doi: 10.1038/eye.2014.78. Epub 2014 Jun 20.
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Clinical and optic coherence tomography findings of focal choroidal excavation in Chinese patients.中国患者局灶性脉络膜凹陷的临床和光相干断层扫描表现。
BMC Ophthalmol. 2014 May 6;14:63. doi: 10.1186/1471-2415-14-63.
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Morphologic features of focal choroidal excavation on spectral domain optical coherence tomography with simultaneous angiography.频域光学相干断层扫描联合血管造影术观察局限性脉络膜凹陷的形态学特征
Retina. 2014 Jul;34(7):1407-14. doi: 10.1097/IAE.0000000000000108.
7
Clinical and spectral-domain optical coherence tomography findings in patients with focal choroidal excavation.局限性脉络膜凹陷患者的临床和谱域光学相干断层扫描表现。
Ophthalmology. 2014 May;121(5):1029-35. doi: 10.1016/j.ophtha.2013.11.043. Epub 2014 Jan 16.
8
Choroidal neovascularization associated with focal choroidal excavation.脉络膜新生血管与局灶性脉络膜凹陷相关。
Am J Ophthalmol. 2014 Mar;157(3):710-8.e1. doi: 10.1016/j.ajo.2013.12.011. Epub 2013 Dec 15.
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Characteristics of central serous chorioretinopathy complicated by focal choroidal excavation.中心性浆液性脉络膜视网膜病变合并局限性脉络膜凹陷的特征
Retina. 2014 Jun;34(6):1216-22. doi: 10.1097/IAE.0000000000000045.
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Focal choroidal excavation complicated by choroidal neovascularization.局限性脉络膜凹陷合并脉络膜新生血管。
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局限性脉络膜凹陷——形态学特征与临床相关性

Focal choroidal excavation-morphological features and clinical correlation.

作者信息

Chung C Y, Li S H, Li K K W

机构信息

Department of Ophthalmology, United Christian Hospital, Kowloon, Hong Kong.

Department of Ophthalmology, Tseung Kwan O Hospital, Kowloon, Hong Kong.

出版信息

Eye (Lond). 2017 Sep;31(9):1373-1379. doi: 10.1038/eye.2017.71. Epub 2017 Apr 28.

DOI:10.1038/eye.2017.71
PMID:28452991
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5601452/
Abstract

PurposeTo describe and correlate the morphological and clinical features of focal choroidal excavation (FCE).MethodsThis is a consecutive case series from the review of the 4436 optical coherence tomography scans performed by Kowloon East Cluster Ophthalmic Service from 1 August 2014-31 January 2016. Statistical analysis was performed on SPSS 18.0 (SPSS, Chicago, IL, USA). A significance level of P<0.05 was taken.ResultsAll 16 patients with FCE had unilateral involvement. The mean age of diagnosis was 52.56±14.00. The mean greatest linear dimension (GLD) of FCE was 636.25±265.11 μm. The mean choroidal thickness was 183.63±52.39 μm. Fourteen FCEs (87.5%) were conforming and two were non-conforming (12.5%). In the eyes with FCE, concurrent macular pathology was present in four cases (25.0%). Tractional pathologies of macular pucker and macular scar corresponded to the two non-conforming FCEs in the series. Polypoidal choroidal vasculopathy (PCV) and lacquer crack had a close topographic relationship with the FCE. The mean GLD was significantly larger in eyes with concurrent macular pathology than those without (878.00 vs 555.67 μm, P=0.029). In the fellow eyes, concurrent macular pathology was present in 5 cases (31.3%): PCV in 3 cases and chronic central serous chorioretinopathy in 2 cases.ConclusionAs a significant proportion of FCE is associated with concurrent macular pathology in the involved or fellow eye, angiography for both eyes is recommended even for asymptomatic cases. The GLD of FCE may have clinical value in risk stratification.

摘要

目的

描述并关联局灶性脉络膜凹陷(FCE)的形态学和临床特征。

方法

这是一项连续病例系列研究,回顾了2014年8月1日至2016年1月31日九龙东联网眼科服务部进行的4436次光学相干断层扫描。使用SPSS 18.0(美国伊利诺伊州芝加哥市SPSS公司)进行统计分析。显著性水平设定为P<0.05。

结果

所有16例FCE患者均为单眼受累。诊断时的平均年龄为52.56±14.00岁。FCE的平均最大线性尺寸(GLD)为636.25±265.11μm。脉络膜平均厚度为183.63±52.39μm。14个FCE(87.5%)符合标准,2个不符合标准(12.5%)。在FCE患眼中,4例(25.0%)同时存在黄斑病变。黄斑皱襞和黄斑瘢痕的牵引性病变与该系列中的2个不符合标准的FCE相对应。息肉样脉络膜血管病变(PCV)和漆裂纹与FCE有密切的地形关系。同时存在黄斑病变的患眼的平均GLD显著大于无黄斑病变的患眼(878.00对555.67μm,P=0.029)。在对侧眼中,5例(31.3%)同时存在黄斑病变:3例为PCV,2例为慢性中心性浆液性脉络膜视网膜病变。

结论

由于相当一部分FCE在患眼或对侧眼中与同时存在的黄斑病变相关,因此即使是无症状病例,也建议对双眼进行血管造影。FCE的GLD在风险分层中可能具有临床价值。