Mokutani Yukako, Hata Taishi, Miyake Yuichiro, Kuroda Hideki, Takahashi Hidekazu, Haraguchi Naotsugu, Nishimura Junichi, Mizushima Tsunekazu, Yamamoto Hirofumi, Doki Yuichiro, Mori Masaki
Department of Surgery, Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka 565-0871, Japan.
Oncol Lett. 2017 Apr;13(4):2765-2769. doi: 10.3892/ol.2017.5755. Epub 2017 Feb 21.
Primary hepatic angiosarcoma is a rare type of tumor with a poor prognosis. To the best of our knowledge, curative surgery of a metastatic gastrointestinal angiosarcoma from a hepatic angiosarcoma has not been reported previously. In the present report, a case of colonic metastasis from a primary hepatic angiosarcoma is discussed. A rapidly growing mass was identified in the liver of an 84-year-old Japanese male who underwent a subsegmentectomy of the liver. Microscopic examination determined that the mass was an angiosarcoma composed of sheets of spindle cells. Immunohistochemical studies confirmed the diagnosis with positive CD31 staining, which indicated the endothelial nature of the malignancy. A total of 14 months following surgery, the patient did not exhibit any symptoms; however, follow-up positron emission tomography and computed tomography images revealed a mass in the cecum. The patient underwent an ileocolectomy, and the microscopic and immunohistochemical findings indicated that the mass was a metastasized colorectal angiosarcoma. At a 4-year post-surgery follow-up appointment the patient was alive with no evidence of recurrence or metastasis.
原发性肝血管肉瘤是一种预后较差的罕见肿瘤。据我们所知，此前尚未有关于肝血管肉瘤转移至胃肠道的血管肉瘤进行根治性手术的报道。在本报告中，讨论了一例原发性肝血管肉瘤发生结肠转移的病例。一名84岁的日本男性在接受肝亚段切除术后，肝脏中发现一个快速生长的肿块。显微镜检查确定该肿块为血管肉瘤，由成片的梭形细胞组成。免疫组织化学研究通过CD31染色阳性证实了诊断，表明该恶性肿瘤具有内皮细胞性质。手术后14个月，患者未出现任何症状；然而，后续的正电子发射断层扫描和计算机断层扫描图像显示盲肠有一个肿块。患者接受了回盲部切除术，显微镜和免疫组织化学检查结果表明该肿块为转移性结直肠血管肉瘤。在术后4年的随访中，患者存活，无复发或转移迹象。
