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灵长类博卡病毒中的基因组重组:不一致性及其他解释

Genomic recombination in primate bocavirus: inconsistency and alternative interpretations.

作者信息

Chong Yee Ling, Ng Kar Hon

机构信息

Faculty of Resource Science and Technology, Universiti Malaysia Sarawak, 94300, Kota Samarahan, Sarawak, Malaysia.

出版信息

Virus Genes. 2017 Dec;53(6):774-777. doi: 10.1007/s11262-017-1459-6. Epub 2017 Apr 29.

Abstract

Human bocavirus (HBoV) is a single-stranded DNA virus in Parvoviridae family, causing respiratory diseases in human. The recent identifications of genomic recombination among the four human bocavirus genotypes and related non-human primate bocaviruses have shed lights into the evolutionary processes underpinning the diversity of primate bocavirus. Among these reports, however, we found inconsistency and possible alternative interpretations of the recombination events. In this study, these recombination events were reviewed, and the related genome sequences were re-analysed, aiming to inform the research community of bocavirus with more consistent knowledge and comprehensive interpretations on the recombination history of primate bocavirus.

摘要

人博卡病毒(HBoV)是细小病毒科的一种单链DNA病毒,可引起人类呼吸道疾病。最近对四种人博卡病毒基因型和相关非人灵长类博卡病毒之间基因组重组的鉴定,为灵长类博卡病毒多样性的进化过程提供了线索。然而,在这些报告中,我们发现了重组事件的不一致性和可能的其他解释。在本研究中,对这些重组事件进行了回顾,并对相关基因组序列进行了重新分析,旨在为博卡病毒研究界提供关于灵长类博卡病毒重组历史更一致的知识和全面的解释。

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