Knyazer Boris, Smolar Jenna, Lazar Isaak, Rosenberg Eli, Tsumi Erez, Lifshitz Tova, Levy Jaime
Department of Ophthalmology, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
International Medical School, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Isr Med Assoc J. 2017 Jan;19(1):34-38.
The identification and prompt diagnosis of Horner syndrome (HS) is essential for preventing permanent damage. HS may arise when a lesion presents anywhere along the three-neuron oculosympathetic pathway that begins at the posterior-lateral nuclei of the hypothalamus all the way through to the orbit. We present four cases and review the literature to familiarize the reader with the identification, diagnosis and treatment of Horner syndrome. The four patients, three adults and one child, were followed for at least 6 months following the initial diagnosis (range 6-18 months). There was partial resolution in three of the four cases, while the fourth resolved completely. There are numerous causes of HS, some of them iatrogenic. While iatrogenic cases of HR are rare in both adults and children, HS is seen more often following surgical procedures. Prompt recognition of the syndrome and correction of the offending agent may prevent permanent damage to the neuronal pathway. It is therefore recommended that practitioners be aware of the risks for development of iatrogenic HS and the signs for early detection.
霍纳综合征（HS）的识别和及时诊断对于预防永久性损伤至关重要。当病变出现在从下丘脑后外侧核一直到眼眶的三神经元眼交感神经通路的任何部位时，可能会出现HS。我们报告4例病例并回顾相关文献，以使读者熟悉霍纳综合征的识别、诊断和治疗。4例患者中，3例为成人，1例为儿童，在初次诊断后至少随访6个月（范围6 - 18个月）。4例中有3例部分缓解，第4例完全缓解。HS有多种病因，其中一些是医源性的。虽然医源性HR在成人和儿童中都很少见，但HS在外科手术后更常见。及时识别该综合征并纠正致病因素可防止对神经通路造成永久性损伤。因此，建议从业者了解医源性HS的发生风险和早期检测的体征。
