Leahy Laura G
J Psychosoc Nurs Ment Health Serv. 2017 May 1;55(5):19-23. doi: 10.3928/02793695-20170420-02.
Understanding the varied delivery systems of today's medications can not only simplify dosing schedules but also improve medication adherence, reduce adverse events and polypharmacy, and increase patients' overall quality of life. Whether a medication is noted as immediate, controlled, delayed, or extended release can influence patient adherence as well as tolerability of the drug. New and novel delivery systems, such as long-acting weekly formulations or biweekly and monthly injectable agents, can offer steady blood levels of the drug, avoiding the daily fluctuations that may lead to side effects. Other delivery systems, such as transdermal patches and extended-release orally disintegrating tablets, may offer convenience for those with gastrointestinal concerns or the inability to swallow tablets or capsules. The current article serves as a primer on drug delivery systems and why they are important to consider when introducing medications to a patient's treatment regimen. [Journal of Psychosocial Nursing and Mental Health Services, 55(5), 19-23.].
了解当今药物的各种给药系统，不仅可以简化给药方案，还能提高用药依从性、减少不良事件和多重用药情况，并提高患者的整体生活质量。一种药物被标注为速释、控释、缓释或长效释放，会影响患者的依从性以及药物的耐受性。新型给药系统，如长效每周制剂或每两周及每月注射剂，可以使药物血药浓度保持稳定，避免可能导致副作用的每日波动。其他给药系统，如透皮贴剂和口腔崩解片，可能为有胃肠道问题或无法吞咽片剂或胶囊的患者提供便利。本文作为药物给药系统的入门介绍，阐述了在患者治疗方案中引入药物时考虑这些系统的重要性。[《心理社会护理与精神卫生服务杂志》，55(5)，19 - 23。]
