Son Eunjung, Kim Ho Kyoung, Kim Hyun Sik, Kim Mee Ree, Kim Dong-Seon
KM Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, Korea.
Department of Food and Nutrition, Chungnam National University, Daejeon, Korea.
Integr Med Res. 2017 Mar;6(1):93-96. doi: 10.1016/j.imr.2016.11.003. Epub 2017 Jan 9.
Propionic acid is a widely used preservative and has been mainly formed by artificial synthesis or fermentation. In the case of natural products, the presence of propionic acid is viewed as a sign that an additive has been introduced for antimicrobial effects.
In this work, the propionic acid that occurs in roots was studied. A quantification method was developed, validated, and showed good linearity, low limit of detection, and limit of quantification values, as well as fine precision and recovery rate. The developed method was applied to the analysis of roots collected in South Korea and China.
The detection rate for all samples was 94.0%. The average concentration was 0.41 ± 0.24 mg/g from the China sample and 0.76 ± 0.28 mg/g from the Korea sample.
This study is the first to report that propionic acid exists in roots and also provides a useful ultra performance liquid chromatography analysis method for its quantification.
丙酸是一种广泛使用的防腐剂，主要通过人工合成或发酵形成。在天然产物中，丙酸的存在被视为添加了具有抗菌作用添加剂的标志。
在本研究中，对根中存在的丙酸进行了研究。开发并验证了一种定量方法，该方法具有良好的线性、低检测限和定量限，以及良好的精密度和回收率。所开发的方法应用于对韩国和中国采集的根样本进行分析。
所有样本的检出率为94.0%。中国样本的平均浓度为0.41±0.24mg/g，韩国样本的平均浓度为0.76±0.28mg/g。
本研究首次报道根中存在丙酸，并为其定量提供了一种有用的超高效液相色谱分析方法。
