Department of Mental Health, Consorci Sanitari de Terrassa (CST), Martí Díez 5, 08224 Terrassa, Barcelona, Spain; Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques Agustí Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Madrid, Spain.
Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques Agustí Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Madrid, Spain; Barcelona Clinic Schizophrenia Unit (BCSU), Clinical Institute of Neurosciences (ICN), Hospital Clínic, Barcelona, Spain.
Psychiatry Res. 2017 Aug;254:198-204. doi: 10.1016/j.psychres.2017.04.065. Epub 2017 Apr 27.
The durability of computer-assisted cognitive remediation (CACR) therapy over time and the cost-effectiveness of treatment remains unclear. The aim of the current study is to investigate the effectiveness of CACR and to examine the use and cost of acute psychiatric admissions before and after of CACR. Sixty-seven participants were initially recruited. For the follow-up study a total of 33 participants were enrolled, 20 to the CACR condition group and 13 to the active control condition group. All participants were assessed at baseline, post-therapy and 12 months post-therapy on neuropsychology, QoL and self-esteem measurements. The use and cost of acute psychiatric admissions were collected retrospectively at four assessment points: baseline, 12 months post-therapy, 24 months post-therapy, and 36 months post-therapy. The results indicated that treatment effectiveness persisted in the CACR group one year post-therapy on neuropsychological and well-being outcomes. The CACR group showed a clear decrease in the use of acute psychiatric admissions at 12, 24 and 36 months post-therapy, which lowered the global costs the acute psychiatric admissions at 12, 24 and 36 months post-therapy. The CACR is durable over at least a 12-month period, and CACR may be helping to reduce health care costs for schizophrenia patients.
计算机辅助认知矫正（CACR）治疗的耐久性以及治疗的成本效益尚不清楚。本研究旨在探讨 CACR 的有效性，并研究 CACR 前后急性精神科住院的使用情况和成本。最初招募了 67 名参与者。在随访研究中，共有 33 名参与者入组，20 名入组 CACR 组，13 名入组活动对照组。所有参与者均在基线、治疗后和治疗后 12 个月接受神经心理学、生活质量和自尊测量。在四个评估点（基线、治疗后 12 个月、治疗后 24 个月和治疗后 36 个月）回顾性收集急性精神科住院的使用情况和费用。结果表明，治疗后 1 年，CACR 组在神经心理学和幸福感方面的治疗效果持续存在。CACR 组在治疗后 12、24 和 36 个月时，急性精神科住院的使用明显减少，这降低了治疗后 12、24 和 36 个月的急性精神科住院总费用。CACR 在至少 12 个月的时间内是持久的，并且 CACR 可能有助于降低精神分裂症患者的医疗保健成本。
