Song G H, Ma Q, Ma S R, Chen C, Wei W W
Cixian Institute for Cancer Prevention and Control, Handan City, Handan 056500, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2017 May 6;51(5):398-402. doi: 10.3760/cma.j.issn.0253-9624.2017.05.006.
To investigate the overall incidence and age distribution of upper digestive tract cancer in Cixian county, and to provide a reliable basis of prevention and treatment for upper gastrointestinal cancer. Collected annual incidence rate among 2003-2012 from Cixian cancer registry and abstracted all incidence rate of upper digestive tract cancer. The age-standardized incidence rate by Chinese standard population (ASR China) was calculated using the national population composition of 2000. The age-standardized incidence rate by world standard population (ASR world) was calculated using the world population composition of 1964 of Segi's. The annual average change (APC) was used to estimate the growth rate of the last two years in comparision with the first two years, which was calculated by Joinpoint regression model. The data was divided into two sections (from 2003 to 2007, and from 2008 to 2012), and the rate difference of different age group was calculated. The crude incidence rate of the digestive tract cancer from 2003 to 2012 was 165.36/100 000 (10 309/6 234 346), which dropped from 170.75/10 100 000 (1 029/602 638) of 2003 to 146.02/100 000 of 2012 (936/640 991).The PC and APC of the crude incidence rate of upper gastrointestinal cancer were-12.96%, and-1.54% (95%-3.22%-0.07%), respectively. The PC and APC of ASR China were-10.83%, and-1.30% (95% 2.54%-0.03%), respectively. The PC and APC of ASR world were-9.82%, and-1.13% (95%-2.20%--0.03%), respectively. The incidence of upper gastrointestinal cancer decreased. The incidence rate of 2003-2007 and 2008-2012 were 171.55/100 000 (5 239/3 048 593), and 159.41/10 000 (5 070/3 180 514), respectively and the rate difference was-12.15/100 000. The decrease of rate difference of 70 to 74 years old was the most (-340.32/100 000) and the increase of rate difference over the age of 85 was the most (447.21/100 000). From 2003 to 2012, the crude incidence of upper digestive tract cancer in Cixian showed a decreasing trend, and the 70-74 years old age group shows the most obvious decline.
为调查磁县上消化道癌的总体发病率及年龄分布情况，为上消化道癌的防治提供可靠依据。收集磁县癌症登记处2003 - 2012年的年发病率，并提取所有上消化道癌的发病率。采用2000年全国人口构成计算中国标准人口年龄标准化发病率（ASR China）。采用1964年Segi世界人口构成计算世界标准人口年龄标准化发病率（ASR world）。用Joinpoint回归模型计算年均变化率（APC），以估计最近两年与前两年相比的增长率。数据分为两个时间段（2003年至2007年和2008年至2012年），计算不同年龄组的率差。2003年至2012年消化道癌的粗发病率为165.36/10万（10309/6234346），从2003年的170.75/10万（1029/602638）降至2012年的146.02/10万（936/640991）。上消化道癌粗发病率的百分比变化（PC）和年均变化率（APC）分别为 - 12.96%和 - 1.54%（95%可信区间 - 3.22% - 0.07%）。ASR China的PC和APC分别为 - 10.83%和 - 1.30%（95%可信区间2.54% - 0.03%）。ASR world的PC和APC分别为 - 9.82%和 - 1.13%（95%可信区间 - 2.20% - - 0.03%）。上消化道癌发病率呈下降趋势。2003 - 2007年和2008 - 2012年的发病率分别为171.55/10万（5239/3048593）和159.41/10万（5070/3180514），率差为 - 12.15/10万。70至74岁年龄组的率差下降最多（ - 340.32/10万），85岁以上年龄组的率差上升最多（447.21/10万）。2003年至2012年，磁县上消化道癌的粗发病率呈下降趋势，其中70 - 74岁年龄组下降最为明显。
