Bonesi Marco, Loizzo Monica R, Acquaviva Rosaria, Malfa Giuseppe A, Aiello Francesca, Tundis Rosa
Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Cosenza. Italy.
Department of Drug Science-Biochemistry Section, University of Catania, 95125, Catania. Italy.
Antiinflamm Antiallergy Agents Med Chem. 2017;16(2):70-86. doi: 10.2174/1871523016666170502121419.
Salvia species are known for their biological properties in many countries and might potentially provide novel therapeutic agents. This review provides an overview of the available literature on the anti-inflammatory and antioxidant effects of Salvia species.
Using bibliographic databases, particularly PubMed, this review aims to add new information to the list of Salvia species, including S. ceratophylla, S. chloroleuca, S. fruticosa, S. lachostachys, S. lavandulifolia, S. miltiorrhiza, S. mirzayanii, S. officinalis, S. plebeia, S. verbenaca, and S. virgata, and their main constituents as promising antiinflammatory and antioxidant agents, highlighting their mode of action.
Salvia species are sources of health-promoting phytochemicals that comprise polyphenols, flavonoids, terpenes and several other constituents. Many studies have indicated that plants from the Salvia genus reduce the oxidative stress and may be able to prevent and/or to treat inflammatory diseases. These potential beneficial effects have been attributed to the presence of compounds that show antioxidant properties and that demonstrated to inhibit the molecular targets of pro-inflammatory mediators in inflammatory responses.
Salvia species and their secondary metabolites may be potential agents to improve the quality of life in patients with inflammatory diseases.
在许多国家，鼠尾草属植物因其生物学特性而闻名，可能会提供新型治疗药物。本综述概述了关于鼠尾草属植物抗炎和抗氧化作用的现有文献。
通过文献数据库，特别是PubMed，本综述旨在为鼠尾草属植物列表增添新信息，包括角叶鼠尾草、绿花鼠尾草、灌木鼠尾草、穗花鼠尾草、薰衣草叶鼠尾草、丹参、米尔扎亚尼鼠尾草、药用鼠尾草、荔枝草、马鞭草叶鼠尾草和假鬃尾草，以及它们作为有前景的抗炎和抗氧化剂的主要成分，突出其作用方式。
鼠尾草属植物是促进健康的植物化学物质的来源，这些物质包括多酚、黄酮类化合物、萜类化合物和其他几种成分。许多研究表明，鼠尾草属植物可减轻氧化应激，可能能够预防和/或治疗炎症性疾病。这些潜在的有益作用归因于存在具有抗氧化特性且已证明能抑制炎症反应中促炎介质分子靶点的化合物。
鼠尾草属植物及其次生代谢产物可能是改善炎症性疾病患者生活质量的潜在药物。
