Phytochemistry and Biological Properties of L.: A Comprehensive Review.

The family Lamiaceae contains several plants used in traditional medicine to fight against different diseases L. () is one of the Lamiaceae species distributed around the Mediterranean regions. This plant exhibits different bioactive properties, including antibacterial, anticancer, antioxidant, antileishmanial, antidiabetic, immunomodulatory, and wound healing. This review was conducted to revise previous studies on addressing its botanical description, geographical distribution, and phytochemical, pharmacological, and toxicological properties. Moreover, the main pharmacological actions of major compounds were well investigated. Literature reports have revealed that possesses a pivotal role in medicinal applications. The findings of this work noted that was found to be rich in chemical compound classes such as terpenoids, phenolics, fatty acids, sterols, and flavonoids. Numerous studies have found that essential oils and extracts have a wide range of biological effects. These results support the potential pharmacological properties of and its traditional uses. This analysis can constitute a scientific basis for further refined studies on its pure secondary metabolites. Therefore, the outcome of the present work may support the perspective of identifying new therapeutical applications with detailed pharmacological mechanisms of to prevent the development of some diseases such as neurodegenerative disorders. However, toxicological investigations into are needed to assess any potential toxicity before it can be further used in clinical studies.