Maartens Aidan
Development. 2017 May 1;144(9):1581-1583. doi: 10.1242/dev.152058.
John Gurdon is a Distinguished Group Leader in the Wellcome Trust/Cancer Research UK Gurdon Institute and Professor Emeritus in the Department of Zoology at the University of Cambridge. In 2012, he was awarded the Nobel Prize in Physiology or Medicine jointly with Shinya Yamanaka for work on the reprogramming of mature cells to pluripotency, and his lab continues to investigate the molecular mechanisms of nuclear reprogramming by oocytes and eggs. We met John in his Cambridge office to discuss his career and hear his thoughts on the past, present and future of reprogramming.
约翰·格登是惠康信托基金会/英国癌症研究所格登研究所的杰出组长,也是剑桥大学动物学系的名誉教授。2012年,他与山中伸弥因在成熟细胞重编程为多能性方面的研究共同获得诺贝尔生理学或医学奖,他的实验室继续研究卵母细胞和卵子进行核重编程的分子机制。我们在他位于剑桥的办公室与约翰见面,讨论他的职业生涯,并聆听他对重编程的过去、现在和未来的看法。