Agarwal Charu, Kaushal Manju, Bhardwaj Minakshi
Department of Pathology, PGIMER, Dr. RML Hospital, New Delhi, India.
J Cytol. 2017 Apr-Jun;34(2):107-109. doi: 10.4103/0970-9371.203576.
Salivary gland cytopathology is a diagnostically challenging area with overlapping cytomorphological features between benign, malignant, and metastatic tumors. We report the case of 45-year-old male who presented with two swellings in right retroauricular and infraauricular region along with a palpable single right cervical lymph node. On ultrasonography of the neck, a possibility of malignant lesion was given. Contrast enhanced computed tomography of the head showed a large well-defined space occupying lesion in right temporooccipital region eroding the skull bone with both extra and intracranial extension. Fine needle aspiration was performed from both swellings and cervical lymph node. Based on cytological features and clinicoradiological examination, a possibility of metastasis from epithelial malignancy (adenocarcinoma) was suggested. The retroauricular region swelling was excised, and a diagnosis of salivary duct carcinoma was given on histopathology. In this article, we discuss the diverse presentation, cytomorphological features, and differential diagnosis of this rare salivary gland tumor.
唾液腺细胞病理学是一个诊断上具有挑战性的领域,良性、恶性和转移性肿瘤之间存在重叠的细胞形态学特征。我们报告了一例45岁男性患者,其右耳后和耳下区域有两个肿物,同时可触及右侧单个颈部淋巴结。颈部超声检查提示可能为恶性病变。头部增强计算机断层扫描显示右侧颞枕部有一个边界清晰的大占位性病变,侵蚀颅骨,有颅外和颅内扩展。对两个肿物及颈部淋巴结进行了细针穿刺抽吸。根据细胞学特征及临床放射学检查,提示可能为上皮性恶性肿瘤(腺癌)转移。切除了耳后区域的肿物,组织病理学诊断为涎腺导管癌。在本文中,我们讨论了这种罕见唾液腺肿瘤的多样表现、细胞形态学特征及鉴别诊断。