Ray Ujjwayini, Ramasubban Suresh, Chakravarty Chandrashish, Goswami Lawni, Dutta Soma
Department of Microbiology, Apollo Gleneagles Hospitals, Kolkata, West Bengal, India.
Department of Critical Care Medicine, Apollo Gleneagles Hospitals, Kolkata, West Bengal, India.
Lung India. 2017 May-Jun;34(3):236-240. doi: 10.4103/lungindia.lungindia_134_15.
Ventilator-associated tracheobronchitis (VAT) is an infective complication of mechanical ventilation and is a part of the spectrum of ventilator-associated respiratory infections. In the Intensive Care Units (ICUs), VAT is a relatively common problem but in comparison to ventilator-associated pneumonia (VAP), much less data are available on VAT and its management.
Patients ventilated for more than 48 hours were screened daily for the development of VAT. Patients were followed up daily until they were extubated, died or discharged from the hospital. The patient demographics, underlying condition, causative organism and resistance patterns were observed.
13.2% of patients developed VAT. The majority patients who developed VAT had underlying neurological problems. The mean time to develop VAT from the time of mechanical ventilation was 7.3 days and from time of ICU admission was 10 days, respectively. Multidrug-resistant (MDR) Acinetobacter sp. and Pseudomonas aeruginosa were the most frequently isolated organisms.
VAT is a common healthcare-associated infection caused mostly by MDR Gram-negative bacteria. Monitoring and active surveillance are required to detect VAT at the earliest to institute appropriate isolation measures and therapy.
呼吸机相关性气管支气管炎（VAT）是机械通气的一种感染性并发症，属于呼吸机相关性呼吸道感染范畴。在重症监护病房（ICU）中，VAT是一个相对常见的问题，但与呼吸机相关性肺炎（VAP）相比，关于VAT及其管理的可用数据要少得多。
对机械通气超过48小时的患者每天进行VAT发生情况筛查。对患者进行每日随访，直至其拔管、死亡或出院。观察患者的人口统计学特征、基础疾病、致病微生物及耐药模式。
13.2%的患者发生了VAT。发生VAT的大多数患者有潜在的神经系统问题。从机械通气开始到发生VAT的平均时间分别为7.3天，从入住ICU开始到发生VAT的平均时间为10天。多重耐药（MDR）不动杆菌属和铜绿假单胞菌是最常分离出的微生物。
VAT是一种常见的医疗相关感染，主要由多重耐药革兰氏阴性菌引起。需要进行监测和主动监测，以便尽早发现VAT，从而采取适当的隔离措施和治疗方法。
