Pandey Arti, Negi Pradeep Singh
a Fruit and Vegetable Technology Department , CSIR-Central Food Technological Research Institute , Mysore , India.
b Academy of Scientific and Innovative Research (AcSIR) , New Delhi , India.
Nat Prod Res. 2018 May;32(10):1189-1192. doi: 10.1080/14786419.2017.1323209. Epub 2017 May 5.
Aqueous extracts of Neolamarckia cadamba fruits prepared at different maturity stages were used for the analysis of various phytochemicals, and their antioxidant and antibacterial activities were determined. Ripe fruit extract had highest phenolics (3.14 mM GAE/ g fruit extract) with caffeic acid, tannic acid, syringic acid and quercetin as major phenolic compounds. The ripe fruit extract showed lowest IC values in DPPH radical scavenging assay (231.33 μg fruit extract/ mL), and highest ABTS radical scavenging activity (111.18 μM TEAC/g). Immature fruit extract showed lowest minimum inhibitory concentration against tested bacteria, and the antibacterial activity was probably due to membrane permeation, as was evident by leakage of genetic material and reduction in propidium iodide uptake by bacterium; and by inhibition of sugar and amino acid uptake. The appreciable amount of phenolic compounds and biological activities in the aqueous extracts of N. cadamba fruits suggests it's potential application as natural preservative.
对不同成熟阶段制备的黄梁木果实水提取物进行了各种植物化学物质分析，并测定了其抗氧化和抗菌活性。成熟果实提取物的酚类物质含量最高（3.14 mM没食子酸当量/克果实提取物），主要酚类化合物为咖啡酸、单宁酸、丁香酸和槲皮素。成熟果实提取物在DPPH自由基清除试验中的IC值最低（231.33微克果实提取物/毫升），ABTS自由基清除活性最高（111.18微摩尔TEAC/克）。未成熟果实提取物对受试细菌的最低抑菌浓度最低，其抗菌活性可能是由于细胞膜渗透，这从遗传物质泄漏和细菌对碘化丙啶摄取减少以及糖和氨基酸摄取受到抑制可以明显看出。黄梁木果实水提取物中可观的酚类化合物含量和生物活性表明其作为天然防腐剂的潜在应用价值。
