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香蕉和番木瓜果皮的植物化学筛选及其药理活性的体外评价

Phytochemical screening and in-vitro evaluation of pharmacological activities of peels of Musa sapientum and Carica papaya fruit.

作者信息

Siddique Sarmad, Nawaz Shamsa, Muhammad Faqir, Akhtar Bushra, Aslam Bilal

机构信息

a Institute of Pharmacy, Physiology and Pharmacology , University of Agriculture , Faisalabad , Pakistan.

出版信息

Nat Prod Res. 2018 Jun;32(11):1333-1336. doi: 10.1080/14786419.2017.1342089. Epub 2017 Jun 18.

Abstract

Aqueous, absolute and 80% ethanolic extract of fruit peels of Musa sapientum and Carica papaya were investigated for their antibacterial activity, measured by disc diffusion method and antioxidant activity, measured by four different methods. Papaya and banana peels were found to contain terpenoids, tannins, alkaloids, saponins steroid, phenols, fixed oils and fats. 80% ethanolic extract of banana peel was found to contain highest total phenolic content (TPC), total flavonoid content (TFC) and antioxidant activity but in papaya peel, highest TPC and reducing activity was shown by water extract while, TFC and radical scavenging activity was given by 80% ethanolic extract. In banana, water extract showed highest antibacterial activity against tested bacteria while in case of papaya, absolute ethanolic extract showed highest antibacterial activity. The present study revealed that peels of banana and papaya fruits are potentially good source of antioxidant and antibacterial agents.

摘要

对香蕉(Musa sapientum)和番木瓜(Carica papaya)果皮的水提取物、无水提取物及80%乙醇提取物进行了抗菌活性(采用纸片扩散法测定)和抗氧化活性(采用四种不同方法测定)的研究。发现木瓜和香蕉皮含有萜类、单宁、生物碱、皂苷、甾体、酚类、固定油和脂肪。发现香蕉皮的80%乙醇提取物含有最高的总酚含量(TPC)、总黄酮含量(TFC)和抗氧化活性,但在木瓜皮中,水提取物显示出最高的TPC和还原活性,而80%乙醇提取物具有最高的TFC和自由基清除活性。在香蕉中,水提取物对受试细菌显示出最高的抗菌活性,而在木瓜中,无水乙醇提取物显示出最高的抗菌活性。本研究表明,香蕉和木瓜果实的果皮可能是抗氧化剂和抗菌剂的良好来源。

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