Webb Christian A, Rosso Isabelle M, Rauch Scott L
From Harvard Medical School and Center for Depression, Anxiety and Stress Research, McLean Hospital, Belmont, MA.
Harv Rev Psychiatry. 2017 May/Jun;25(3):114-122. doi: 10.1097/HRP.0000000000000139.
The World Health Organization estimates that during a given 12-month period, approximately 34 million people suffering from major depressive disorder go untreated in Europe and the Americas alone. Barriers to treatment include geographic distance, lack of mental health insurance, prohibitive cost of treatment, long wait-lists, and perceived stigma. Over the past two decades, Internet-based cognitive-behavioral therapy (iCBT) programs have proliferated. A growing body of research supports the efficacy of iCBT for depression and other psychiatric conditions, and these programs may help address barriers that hinder access to effective treatment. The present review describes common iCBT programs along with the evidence base supporting their efficacy in reducing symptoms of depression, reviews research on moderators of treatment response, and provides suggestions for future directions in research and care.
世界卫生组织估计，仅在欧洲和美洲，在特定的12个月期间，约有3400万患有重度抑郁症的人未得到治疗。治疗障碍包括地理距离、缺乏心理健康保险、治疗费用过高、等待名单过长以及存在耻辱感。在过去二十年中，基于互联网的认知行为疗法（iCBT）项目激增。越来越多的研究支持iCBT对抑郁症和其他精神疾病的疗效，这些项目可能有助于解决阻碍获得有效治疗的障碍。本综述描述了常见的iCBT项目以及支持其减轻抑郁症状疗效的证据基础，回顾了关于治疗反应调节因素的研究，并为未来的研究和护理方向提供了建议。
