Carnethon Mercedes R, Ayala Guadalupe X, Bangdiwala Shrikant I, Bishop Virginia, Daviglus Martha L, Delamater Alan M, Gallo Linda C, Perreira Krista, Pulgaron Elizabeth, Reina Samantha, Talavera Gregory A, Van Horn Linda H, Isasi Carmen R
Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL.
College of Health and Human Services, San Diego State University and the Institute for Behavioral and Community Health, San Diego, CA.
Ann Epidemiol. 2017 Apr;27(4):260-268.e2. doi: 10.1016/j.annepidem.2017.03.001. Epub 2017 Mar 31.
Hispanic/Latinos have a high burden of cardiovascular disease (CVD) risk factors which may begin at young ages. We tested the association of CVD risk factors between Hispanic/Latino parents and their children.
We conducted a cross-sectional study in the Hispanic Community Health Study/Study of Latinos Youth study. Girls (n = 674) and boys (n = 667) aged 8 to 16 years (mean age 12.1 years) and their parents (n = 942) had their CVD risk factors measured.
CVD risk factors in parents were significantly positively associated with those same risk factors among youth. After adjustment for demographic characteristics, diet and physical activity, obese parents were significantly more likely to have youth who were overweight (odds ratios [ORs], 2.39; 95% confidence interval [CI], 1.20-4.76) or obese (OR, 6.16; 95% CI, 3.23-11.77) versus normal weight. Dyslipidemia among parents was associated with 1.98 higher odds of dyslipidemia among youth (95% CI, 1.37-2.87). Neither hypertension nor diabetes was associated with higher odds of high blood pressure or hyperglycemia (prediabetes or diabetes) in youth. Findings were consistent by sex and in younger (age <12 years) versus older (≥12 years) youth.
Hispanic/Latino youth share patterns of obesity and CVD risk factors with their parents, which portends high risk for adult CVD.
西班牙裔/拉丁裔人群心血管疾病（CVD）危险因素负担较重，这些危险因素可能在年轻时就已出现。我们对西班牙裔/拉丁裔父母及其子女的CVD危险因素之间的关联进行了测试。
我们在西班牙裔社区健康研究/拉丁裔青年研究中开展了一项横断面研究。对年龄在8至16岁（平均年龄12.1岁）的女孩（n = 674）和男孩（n = 667）及其父母（n = 942）进行了CVD危险因素测量。
父母的CVD危险因素与青少年中的相同危险因素显著正相关。在对人口统计学特征、饮食和身体活动进行调整后，肥胖父母的子女超重（优势比[OR]，2.39；95%置信区间[CI]，1.20 - 4.76）或肥胖（OR，6.16；95% CI，3.23 - 11.77）的可能性显著高于正常体重的父母。父母血脂异常与青少年血脂异常的较高优势比（1.98）相关（95% CI，1.37 - 2.87）。高血压和糖尿病均与青少年高血压或高血糖（糖尿病前期或糖尿病）的较高优势比无关。按性别以及较年轻（年龄<12岁）与较年长（≥12岁）青少年分层的研究结果一致。
西班牙裔/拉丁裔青少年与其父母共享肥胖和CVD危险因素模式，这预示着其成年后患心血管疾病的高风险。
