García-Herrera Adriana, Calonje Eduardo
Department of Pathology, Hospital Clínic de Barcelona, Villarroel, 170, Escalera 3, Planta 5, Barcelona 08036, Spain.
Dermatopathology Laboratory, St John's Institute of Dermatology, St Thomas' Hospital, South Wing, Staircase C, Westminster Bridge Road, London SE1 7EH, UK.
Surg Pathol Clin. 2017 Jun;10(2):409-427. doi: 10.1016/j.path.2017.01.003. Epub 2017 Mar 28.
Primary cutaneous cytotoxic lymphomas are T-cell or natural killer-cell lymphomas that express 1 or more cytotoxic markers. These neoplasms constitute a spectrum of diseases. In this review, an overview of clinical, morphologic, and phenotypical features of each subtype is provided. Differential diagnosis is discussed with attention to scenarios in which diagnostic difficulties are most frequently encountered.
原发性皮肤细胞毒性淋巴瘤是表达一种或多种细胞毒性标志物的T细胞或自然杀伤细胞淋巴瘤。这些肿瘤构成了一系列疾病。在本综述中，提供了各亚型的临床、形态学和表型特征概述。讨论了鉴别诊断，并关注最常遇到诊断困难的情况。
