Takeuchi Hikaru, Kawashima Ryuta
Division of Developmental Cognitive Neuroscience, Institute of Development, Aging and Cancer, Tohoku University.
Brain Nerve. 2017 May;69(5):547-556. doi: 10.11477/mf.1416200781.
Voxel-based morphometry has been used to investigate the associations between regional gray and white matter volume and cognitive function. The manuscript introduces these studies' methods, cautions, results, and problems related to the reports of the results. In many studies of ours that investigating these associations using the huge sample size and robust statistics, the associations were weak and wide spread in the brain. These patterns of results suggest the difficulty in finding the specific neural bases that underlie individual cognitive functions through VBM.
基于体素的形态测量学已被用于研究局部灰质和白质体积与认知功能之间的关联。该手稿介绍了这些研究的方法、注意事项、结果以及与结果报告相关的问题。在我们许多使用大样本量和稳健统计方法来研究这些关联的研究中，这些关联在大脑中很微弱且分布广泛。这些结果模式表明，通过基于体素的形态测量学来找到构成个体认知功能基础的特定神经基础存在困难。
