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刚果绝经前后女性高血压前期的患病率及危险因素

Prevalence and risk factors of pre-hypertension in Congolese pre and post menopausal women.

作者信息

Muchanga Mjs, Lepira F B, Tozin R, Mbelambela E P, Ngatu N R, Sumaili E K, Makulo J R, Suganuma N

机构信息

Department of Obstetrics and Gynecology, Kinshasa University Hospital, Kinshasa, Democratic Republic of the Congo.

Department of Environmental Medicine, Kochi Medical School, Kochi University, Kochi, Japan.

出版信息

Afr Health Sci. 2016 Dec;16(4):979-985. doi: 10.4314/ahs.v16i4.14.

Abstract

OBJECTIVES

We aimed to assess the prevalence of prehypertension and its associated factors in a population of Congolese pre and postmenopausal women.

METHODS

We had consecutively recruited 200 women (100 premenopausal and 100 postmenopausal) aged 40 - 60 years at the department of Gynecology and Obstetrics, University of Kinshasa Hospital, and AKRAM Medical Center in Kinshasa, DRC. An interview was carried out using a questionnaire that comprised questions related to lifestyle, menses characteristics, medical history of diabetes, CVD, hypertension, current antihypertensive medication and use of traditional medicine. In addition, physical examination and biological measurements were performed. Multivariate logistic regression analysis was used to assess associated factors with prehypertension.

RESULTS

Of the participants, 34% were normotensive, 38.5 % prehypertensive and 27.5% hypertensive. Compared to normal blood pressure, prehypertension was common in the older (age>50 years of age) women. Menopause, the use of traditional medicine and older age were associated with prehypertension. However, only menopause (aOR: 2.71; 95%CI: 1.10-3.52) and the use of traditional medicine (aOR: 2.24; 95% CI: 1.07-4.7) remained associated with prehypertension in a multivariate logistic regression analysis.

CONCLUSION

This study showed that prehypertension is common among Congolese menopausal women, and that menopause and the use of traditional medicine were the main factors associated with prehypertension.

摘要

目的

我们旨在评估刚果绝经前后女性人群中高血压前期的患病率及其相关因素。

方法

我们在金沙萨大学医院妇产科以及刚果民主共和国金沙萨的阿克拉姆医疗中心连续招募了200名年龄在40 - 60岁之间的女性(100名绝经前女性和100名绝经后女性)。使用一份问卷进行访谈,问卷包含与生活方式、月经特征、糖尿病病史、心血管疾病、高血压、当前抗高血压药物使用情况以及传统药物使用情况相关的问题。此外,还进行了体格检查和生物测量。采用多因素逻辑回归分析来评估高血压前期的相关因素。

结果

在参与者中,34%为血压正常,38.5%为高血压前期,27.5%为高血压。与正常血压相比,高血压前期在年龄较大(年龄>50岁)的女性中更为常见。绝经、传统药物的使用和年龄较大与高血压前期相关。然而,在多因素逻辑回归分析中,只有绝经(调整后比值比:2.71;95%置信区间:1.10 - 3.52)和传统药物的使用(调整后比值比:2.24;95%置信区间:1.07 - 4.7)仍与高血压前期相关。

结论

本研究表明,高血压前期在刚果绝经女性中较为常见,绝经和传统药物的使用是与高血压前期相关的主要因素。

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