Charernboon Thammanard, Patumanond Jayanton
Department of Psychiatry, Faculty of Medicine, Thammasat University, Pathumthani, Thailand.
Division of Clinical Epidemiology, Faculty of Medicine, Thammasat University, Pathumthani, Thailand.
Ment Illn. 2017 Mar 22;9(1):7054. doi: 10.4081/mi.2017.7054.
Impairments in social cognitions in schizophrenia are increasingly reported in the last decade but only a few studies have come from Asia. The objective of the study was to evaluated emotion perception, theory of mind and social knowledge in people with schizophrenia compared to healthy controls. Participants were 36 clinically stable outpatients with schizophrenia and 36 normal controls with comparable age and level of education. We administered general neurocognition test (the Addenbrooke's Cognitive Examination), emotion perception (the Faces Test), theory of mind (the Eyes Test) and social knowledge (the Situational Features Recognition Test; SFRT). Schizophrenia patients displayed obvious impairment in all three social cognition domains the Faces Test [13.7 (2.9) 15.7 (1.9), P=0.001], the Eyes Test [18.9 (4.4) 23.5 (4.4), P<0.001] and SFRT [0.85 (0.09) 0.9 (0.05), P=0.002]. The performances on three social cognition tests did not correlate with positive symptoms. Only the Faces Test seemed to be related to negative symptoms. The results demonstrated that there are deficits of social cognitions in schizophrenia even in a clinically stable population.
在过去十年中,越来越多的研究报道了精神分裂症患者存在社会认知障碍,但来自亚洲的研究却很少。本研究的目的是比较精神分裂症患者与健康对照者在情绪感知、心理理论和社会知识方面的差异。研究对象为36名临床症状稳定的精神分裂症门诊患者和36名年龄及教育程度相当的正常对照者。我们进行了一般神经认知测试(Addenbrooke认知检查)、情绪感知测试(面部表情测试)、心理理论测试(眼神测试)和社会知识测试(情境特征识别测试;SFRT)。精神分裂症患者在所有三个社会认知领域均表现出明显受损:面部表情测试[13.7(2.9)对15.7(1.9),P = 0.001]、眼神测试[18.9(4.4)对23.5(4.4),P < 0.001]和SFRT[0.85(0.09)对0.9(0.05),P = 0.002]。三项社会认知测试的表现与阳性症状无关。只有面部表情测试似乎与阴性症状有关。结果表明,即使在临床症状稳定的人群中,精神分裂症患者也存在社会认知缺陷。