糖尿病患者初次全膝关节置换术的临床疗效评估
Clinical Outcome Evaluation of Primary Total Knee Arthroplasty in Patients with Diabetes Mellitus.
作者信息
Liu Pengcheng, Liu Junfeng, Xia Kuo, Chen Liyang, Wu Xing
机构信息
Department of Orthopedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China (mainland).
出版信息
Med Sci Monit. 2017 May 9;23:2198-2202. doi: 10.12659/msm.901720.
BACKGROUND The aim of this study was to evaluate the safety and clinical outcome of primary total knee arthroplasty in patients with diabetes mellitus. MATERIAL AND METHODS Among the patients who were treated with total knee arthroplasty, there were 98 patients (116 knees) associated with diabetes. Osteoarthritis was diagnosed in 90 patients and rheumatoid arthritis was diagnosed in 8 patients. Various degrees of preoperative knee deformities were found in 82 knees. The average fasting blood glucose was 9.8±3.6 mmol/L at admission. RESULTS The clinical efficacy of TKA was satisfactory in patients with diabetes mellitus. Diabetic patients do not seem to have a significantly higher risk for infection and DVT after TKA. At the final follow-up time point, no prosthesis loosening was found and no revision was needed in any patients. The mean HSS scores increased and the excellent rate was 100%. CONCLUSIONS Using perioperative comprehensive assessment of heart and lung function, and by preventing infection and the formation of DVT, we achieved satisfactory early clinical efficacy of TKA in patients with diabetes mellitus.
背景 本研究旨在评估糖尿病患者初次全膝关节置换术的安全性及临床疗效。材料与方法 在接受全膝关节置换术治疗的患者中，有98例患者（116膝）合并糖尿病。其中90例诊断为骨关节炎，8例诊断为类风湿关节炎。82膝存在不同程度的术前膝关节畸形。入院时平均空腹血糖为9.8±3.6 mmol/L。结果 糖尿病患者全膝关节置换术的临床疗效满意。糖尿病患者全膝关节置换术后感染及深静脉血栓形成风险似乎并未显著升高。在末次随访时间点，未发现假体松动，所有患者均无需翻修。HSS评分均值升高，优良率为100%。结论 通过围手术期心肺功能综合评估，预防感染及深静脉血栓形成，我们在糖尿病患者全膝关节置换术中取得了满意的早期临床疗效。
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