Father Muller Medical College Hospital, Mangalore, India.
Int J Dermatol. 2017 Sep;56(9):957-960. doi: 10.1111/ijd.13633. Epub 2017 May 8.
Dermatosis papulosa nigra (DPN) is a benign cutaneous condition which commonly occurs in dark-skinned people, especially Asians and African Americans. Owing to its benign nature and rarity, very few studies have been conducted to date, and dermoscopic studies are practically nonexistent.
To study the clinical and epidemiological characteristics of patients with dermatosis papulosa nigra (DPN) and to correlate the clinical findings with dermoscopic and histopathological findings in DPN.
A total of 100 patients attending the Dermatology outpatient department at Father Muller Medical College, Mangalore, India, with clinically diagnosed dermatosis papulosa nigra were included in the study. Histopathology and dermoscopic evaluation of the lesions were done, and the characteristics seen were noted.
Earlier onset of lesions was noted in our study, i.e. onset in the 4th decade as compared to the 6th decade in most other studies. A female preponderance, positive family history, history of sun exposure, and involvement of the head and neck were other significant associations. Histopathology revealed an acanthotic variant in all the lesions that were biopsied. The predominant dermoscopic finding was fissures and ridges of the cerebriform pattern followed by comedo-like openings.
Dermatosis papulosa nigra is a benign unaesthetic condition seen in Fitzpatrick skin types IV-VI. The diagnosis is mainly clinical; however, in a few cases histopathology and dermoscopy aid in differentiating it from other benign and malignant tumors. Dermoscopy, in particular, being a noninvasive investigative moiety is a rapid and accurate diagnostic tool.
色素性黑棘皮病（DPN）是一种良性皮肤疾病，常见于深色皮肤人群，尤其是亚洲人和非裔美国人。由于其良性性质和罕见性，迄今为止很少有研究进行，并且皮肤镜检查实际上也不存在。
研究色素性黑棘皮病（DPN）患者的临床和流行病学特征，并将临床发现与 DPN 的皮肤镜和组织病理学发现相关联。
本研究共纳入 100 名在印度芒格洛尔 Father Muller 医学院皮肤科门诊就诊的经临床诊断为色素性黑棘皮病的患者。对病变进行组织病理学和皮肤镜评估，并记录所观察到的特征。
与大多数其他研究相比，我们的研究中病变的发病年龄更早，即第 4 个十年，而不是第 6 个十年。女性发病倾向更高，有家族史，有阳光暴露史，以及头颈部受累也是其他重要的关联因素。组织病理学显示所有活检病变均为棘层肥厚型。最主要的皮肤镜表现是脑回样形态的裂隙和脊，其次是粉刺样开口。
色素性黑棘皮病是一种良性、影响美观的疾病，常见于 Fitzpatrick 皮肤类型 IV-VI。诊断主要依靠临床，然而在少数情况下，组织病理学和皮肤镜检查有助于将其与其他良性和恶性肿瘤区分开来。皮肤镜检查，特别是一种非侵入性的检查方法，是一种快速而准确的诊断工具。
