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本文引用的文献

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Carbon dioxide laser ablation of dermatosis papulosa nigra: high satisfaction and few complications in patients with pigmented skin.二氧化碳激光消融治疗黑色丘疹性皮肤病:色素沉着皮肤患者满意度高且并发症少。
Lasers Med Sci. 2016 Apr;31(3):593-5. doi: 10.1007/s10103-016-1906-y. Epub 2016 Feb 11.
2
What's new in objective assessment and treatment of facial hyperpigmentation?客观评估和治疗面部色素沉着有哪些新进展?
Dermatol Clin. 2014 Apr;32(2):123-35. doi: 10.1016/j.det.2013.12.008.
3
Dermatologic conditions in skin of color: part II. Disorders occurring predominately in skin of color.皮肤色素沉着的皮肤状况:第二部分。主要发生在皮肤色素沉着的疾病。
Am Fam Physician. 2013 Jun 15;87(12):859-65.
4
Postprocedural wound-healing efficacy following removal of dermatosis papulosa nigra lesions in an African American population: a comparison of a skin protectant ointment and a topical antibiotic.在非裔美国人中切除色素性丘疹性黑变病皮损后的术后伤口愈合功效:一种皮肤保护软膏与一种局部抗生素的比较。
J Am Acad Dermatol. 2011 Mar;64(3 Suppl):S30-5. doi: 10.1016/j.jaad.2010.11.009. Epub 2011 Jan 17.
5
FGFR3 and PIK3CA mutations in stucco keratosis and dermatosis papulosa nigra.钉板状角化病和色素性乳头状瘤病中 FGFR3 和 PIK3CA 突变。
Br J Dermatol. 2010 Mar;162(3):508-12. doi: 10.1111/j.1365-2133.2009.09488.x. Epub 2009 Sep 1.
6
Dermatosis papulosa nigra treatment with fractional photothermolysis.用分次光热解治疗黑色丘疹性皮病。
Dermatol Surg. 2009 Nov;35(11):1840-3. doi: 10.1111/j.1524-4725.2009.01302.x. Epub 2009 Oct 1.
7
Comparison of electrodesiccation and potassium-titanyl-phosphate laser for treatment of dermatosis papulosa nigra.电干燥法与磷酸钛氧钾激光治疗黑色丘疹性皮病的比较
Dermatol Surg. 2009 Jul;35(7):1079-83. doi: 10.1111/j.1524-4725.2009.01186.x. Epub 2009 May 15.
8
Dermatosis papulosa nigra in Dakar, Senegal.塞内加尔达喀尔的黑色丘疹性皮肤病。
Int J Dermatol. 2007 Oct;46 Suppl 1:45-7. doi: 10.1111/j.1365-4632.2007.03465.x.
9
The prevalence of seborrhoeic keratoses in an Australian population: does exposure to sunlight play a part in their frequency?澳大利亚人群中脂溢性角化病的患病率:阳光暴露对其发生频率有影响吗?
Br J Dermatol. 1997 Sep;137(3):411-4.
10
Dermatology Life Quality Index (DLQI)--a simple practical measure for routine clinical use.皮肤病生活质量指数(DLQI)——一种用于日常临床的简单实用测量方法。
Clin Exp Dermatol. 1994 May;19(3):210-6. doi: 10.1111/j.1365-2230.1994.tb01167.x.

黑色丘疹性皮病:一项生活质量调查研究。

Dermatosis Papulosa Nigra: A Quality of Life Survey Study.

作者信息

Uwakwe Laura N, Souza Brianna DE, Subash Jacob, McMichael Amy J

机构信息

All authors are with the Department of Dermatology at Wake Forest School of Medicine in Winston-Salem, North Carolina.

出版信息

J Clin Aesthet Dermatol. 2020 Feb;13(2):17-19. Epub 2020 Feb 1.

PMID:32308781
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7158914/
Abstract

Dermatosis papulosa nigra (DPN) is a skin condition characterized by pigmented sessile and pedunculated papules on the body, particularly on the face and other sun-exposed areas, that can cause cosmetic disfigurement and varying degrees of distress and psychosocial concern among patients. We sought to evaluate the effect of DPN on quality of life (QoL). A 39-item questionnaire was administered to 50 African-American (AA) adults, 48 women and two men, with an average age of 51.7 years and visible DPN lesions at a dermatology clinic. We collected demographic information, family history, prior treatment, as well as type(s), frequency, duration of lesions, and attitudes about lesions. Dermatologic QoL (DLQI) survey scores were used to quantify the effect that DPN had on QoL. RESULTS: Most subjects reported lesions on the face (86%); 49 percent reported between 10 to 30 lesions on the body. The average age of diagnosis was 44.7 years (±15.51 years). Further, 84 percent of subjects reported having a firstdegree relative with DPN. Most patients reported little to no symptoms from their DPN (82%), while 36 percent had previously visited a physician due to their DPN. Electrocautery and cryosurgery were the most common methods of DPN removal. All subjects who had their DPN lesions removed reported improvement in the appearance of their skin. The average (standard deviation) DLQI score was six points (±5.42 points), which indicates that DPN has a moderate effect on QoL. Our study results reveal the high likelihood of a family history of DPN in subjects with the condition. Overall, most subjects reported few symptoms of DPN and their QoL was only moderately affected by DPN. Still, patients might benefit from the removal of DPN lesions.

摘要

黑色丘疹性皮病(DPN)是一种皮肤疾病,其特征是身体上出现色素沉着的无柄和有蒂丘疹,尤其是在面部和其他暴露于阳光下的部位,这可能会导致患者出现容貌毁损以及不同程度的痛苦和心理社会问题。我们试图评估DPN对生活质量(QoL)的影响。对50名非裔美国(AA)成年人进行了一项包含39个项目的问卷调查,其中48名女性和2名男性,平均年龄为51.7岁,且在皮肤科诊所患有可见的DPN病变。我们收集了人口统计学信息、家族史、既往治疗情况,以及病变的类型、频率、持续时间和对病变的态度。使用皮肤病生活质量(DLQI)调查评分来量化DPN对生活质量的影响。结果:大多数受试者报告面部有病变(86%);49%的受试者报告身体上有10至30个病变。诊断的平均年龄为44.7岁(±15.51岁)。此外,84%的受试者报告有DPN的一级亲属。大多数患者报告其DPN几乎没有症状(82%),而36%的患者此前因DPN看过医生。电灼术和冷冻手术是最常见的DPN去除方法。所有去除DPN病变 的受试者均报告皮肤外观有所改善。平均(标准差)DLQI评分为6分(±5.42分),这表明DPN对生活质量有中度影响。我们的研究结果显示,患有DPN的受试者有家族病史的可能性很高。总体而言,大多数受试者报告DPN症状较少,其生活质量仅受到DPN的中度影响。尽管如此。患者可能会从去除DPN病变中受益。