Uwakwe Laura N, Souza Brianna DE, Subash Jacob, McMichael Amy J
All authors are with the Department of Dermatology at Wake Forest School of Medicine in Winston-Salem, North Carolina.
J Clin Aesthet Dermatol. 2020 Feb;13(2):17-19. Epub 2020 Feb 1.
Dermatosis papulosa nigra (DPN) is a skin condition characterized by pigmented sessile and pedunculated papules on the body, particularly on the face and other sun-exposed areas, that can cause cosmetic disfigurement and varying degrees of distress and psychosocial concern among patients. We sought to evaluate the effect of DPN on quality of life (QoL). A 39-item questionnaire was administered to 50 African-American (AA) adults, 48 women and two men, with an average age of 51.7 years and visible DPN lesions at a dermatology clinic. We collected demographic information, family history, prior treatment, as well as type(s), frequency, duration of lesions, and attitudes about lesions. Dermatologic QoL (DLQI) survey scores were used to quantify the effect that DPN had on QoL. RESULTS: Most subjects reported lesions on the face (86%); 49 percent reported between 10 to 30 lesions on the body. The average age of diagnosis was 44.7 years (±15.51 years). Further, 84 percent of subjects reported having a firstdegree relative with DPN. Most patients reported little to no symptoms from their DPN (82%), while 36 percent had previously visited a physician due to their DPN. Electrocautery and cryosurgery were the most common methods of DPN removal. All subjects who had their DPN lesions removed reported improvement in the appearance of their skin. The average (standard deviation) DLQI score was six points (±5.42 points), which indicates that DPN has a moderate effect on QoL. Our study results reveal the high likelihood of a family history of DPN in subjects with the condition. Overall, most subjects reported few symptoms of DPN and their QoL was only moderately affected by DPN. Still, patients might benefit from the removal of DPN lesions.
黑色丘疹性皮病(DPN)是一种皮肤疾病,其特征是身体上出现色素沉着的无柄和有蒂丘疹,尤其是在面部和其他暴露于阳光下的部位,这可能会导致患者出现容貌毁损以及不同程度的痛苦和心理社会问题。我们试图评估DPN对生活质量(QoL)的影响。对50名非裔美国(AA)成年人进行了一项包含39个项目的问卷调查,其中48名女性和2名男性,平均年龄为51.7岁,且在皮肤科诊所患有可见的DPN病变。我们收集了人口统计学信息、家族史、既往治疗情况,以及病变的类型、频率、持续时间和对病变的态度。使用皮肤病生活质量(DLQI)调查评分来量化DPN对生活质量的影响。结果:大多数受试者报告面部有病变(86%);49%的受试者报告身体上有10至30个病变。诊断的平均年龄为44.7岁(±15.51岁)。此外,84%的受试者报告有DPN的一级亲属。大多数患者报告其DPN几乎没有症状(82%),而36%的患者此前因DPN看过医生。电灼术和冷冻手术是最常见的DPN去除方法。所有去除DPN病变 的受试者均报告皮肤外观有所改善。平均(标准差)DLQI评分为6分(±5.42分),这表明DPN对生活质量有中度影响。我们的研究结果显示,患有DPN的受试者有家族病史的可能性很高。总体而言,大多数受试者报告DPN症状较少,其生活质量仅受到DPN的中度影响。尽管如此。患者可能会从去除DPN病变中受益。