Rowett Institute, University of Aberdeen, Foresterhill, Aberdeen, UK.
Rowett Institute, University of Aberdeen, Foresterhill, Aberdeen, UK.
Curr Opin Microbiol. 2017 Aug;38:59-65. doi: 10.1016/j.mib.2017.04.005. Epub 2017 May 6.
What we eat influences the species composition of our gut microbiota. This is not only because diet composition determines the supply of substrates for microbial growth (in the form of dietary residue, mainly fibre, that reaches the large intestine) but also because of impacts on gut transit and the gut environment. In turn the metabolic activities of the gut microbiota, which have important health consequences, are influenced by diet and diet-driven changes in microbiota composition. Better understanding of the metabolic capabilities and host-interactions of dominant members of the gut microbiota will aid our ability to improve human health through diet.
我们所吃的食物会影响肠道微生物群的物种组成。这不仅是因为饮食组成决定了微生物生长的基质供应(以到达大肠的膳食纤维为主的饮食残渣形式),还因为它会对肠道转运和肠道环境产生影响。反过来,肠道微生物群的代谢活动对健康有重要影响,而这些代谢活动又受到饮食和饮食引起的微生物群组成变化的影响。更好地了解肠道微生物群中的优势成员的代谢能力和与宿主的相互作用,将有助于我们通过饮食来改善人类健康。