肥胖与感染的关联：一项回顾性研究。
Association of obesity with infection: A retrospective study.
作者信息
Xu Mei-Yan, Liu Lan, Yuan Bao-Shi, Yin Jian, Lu Qing-Bin
机构信息
Mei-Yan Xu, Jian Yin, Department of Nutrition, Aerospace Center Hospital, Beijing 100049, China.
出版信息
World J Gastroenterol. 2017 Apr 21;23(15):2750-2756. doi: 10.3748/wjg.v23.i15.2750.
AIM
To explore the association between () infection and obesity/weight gain in a Chinese population.
METHODS
Our primary outcome was the change in body mass index (BMI). The generalized linear models were used to explore the association between infection and the change of BMI, and the logistic regression models were used to explore the association between infection and obesity.
RESULTS
A total of 3039 subjects were recruited and analyzed, of which 12.8% were obese. The prevalence of infection was 53.9% (1639/3039) overall and 54.6% (212/388) in the obese subjects. The change of BMI in the (+) group was not significantly higher than that in the (-) group after adjustment for potential confounding factors [RR = 0.988, 95%CI: 0.924-1.057, = 0.729]. The prevalence of obesity decreased 1.1% in the (+) group and 0.5% in the (-) group. The RR of infection for obesity was 0.831 (95%CI: 0.577-1.197, = 0.321) after the adjustment.
CONCLUSION
infection was not associated with overweight/obesity observed from the retrospective study in this Chinese population.
目的
探讨中国人群中（）感染与肥胖/体重增加之间的关联。
方法
我们的主要结局是体重指数（BMI）的变化。采用广义线性模型探讨（）感染与BMI变化之间的关联，采用逻辑回归模型探讨（）感染与肥胖之间的关联。
结果
共纳入3039名受试者进行分析，其中12.8%为肥胖者。总体（）感染率为53.9%（1639/3039），肥胖受试者中为54.6%（212/388）。在调整潜在混杂因素后，（）阳性组的BMI变化并不显著高于（）阴性组[RR = 0.988，95%CI：0.924 - 1.057，P = 0.729]。（）阳性组肥胖患病率下降1.1%，（）阴性组下降0.5%。调整后，（）感染导致肥胖的RR为0.831（95%CI：0.577 - 1.197，P = 0.321）。
结论
从这项针对中国人群的回顾性研究中观察到，（）感染与超重/肥胖无关。
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