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有与没有黏弹剂装置的超声乳化术对手术结果的影响。

Effects of phacoemulsification with versus without viscoelastic devices on surgical outcomes.

作者信息

Taşkın İbrahim, Aslan Lokman

机构信息

Ophthalmology Department, Maya Eye Clinic, Adana, Turkey.

Department of Ophthalmology, Faculty of Medicine, KSU Kahramanmaras Sutcu Imam University, Kahramanmaras, 46050, Turkey.

出版信息

Int Ophthalmol. 2018 Feb;38(1):5-10. doi: 10.1007/s10792-017-0546-y. Epub 2017 May 9.

Abstract

PURPOSE

The aim of this study is to report surgical outcomes in patients undergoing phacoemulsification surgery (PE) with versus without ophthalmic viscosurgical devices (OVDs).

METHODS

This is a comparative case series study. In total, 145 patients who performed PE with OVDs in 68 eyes (Group 1) and without OVD in 77 eyes (Group 2) were enrolled. A comprehensive ophthalmological examination was performed including slit-lamp, fundus examination. Best-corrected visual acuity (BCVA), intraocular pressure (IOP) specular endothelial microscopy (SM), and ultrasound pachymetry (UP) were also measured before surgery and at four-time points postoperatively. The differences in baseline characteristics as well as in outcomes were compared between the two groups.

RESULTS

The mean BCVA was 0.41 ± 0.26 logMAR in Group 1 and 0.54 ± 0.34 in Group 2 at postoperative first day, with a significant difference (p < 0.01). The mean BCVA, IOP, and UP at 6 months did not differ between the groups. The mean baseline and postoperative SMs were 2063 and 1910 cells/mm, respectively, and the endothelial cell loss (ECL) was 153.89 ± 189 in Group 1. The mean baseline and postoperative SMs were 2153 and 1948 cells/mm, respectively, and the ECL was 205 ± 200 in Group 2. The difference between the groups was not statistically significant (p = 0.105).

CONCLUSIONS

The ECL seemed to be higher in the Group 2, but the difference was not significant. The final clinical outcomes were similar between the groups. In selected cases, PE without OVD may be preferable to reduce the cost of surgery in places with low economic status and to prevent side-effects of these devices.

摘要

目的

本研究旨在报告行超声乳化手术(PE)时使用与不使用眼科粘弹剂(OVDs)的患者的手术结果。

方法

这是一项对比病例系列研究。共纳入145例患者,其中68眼行使用OVDs的PE手术(第1组),77眼行不使用OVD的PE手术(第2组)。进行了包括裂隙灯、眼底检查在内的全面眼科检查。术前及术后四个时间点还测量了最佳矫正视力(BCVA)、眼压(IOP)、镜面内皮显微镜检查(SM)和超声测厚(UP)。比较了两组的基线特征及结果差异。

结果

术后第一天,第1组的平均BCVA为0.41±0.26 logMAR,第2组为0.54±0.34,差异有统计学意义(p<0.01)。两组在6个月时的平均BCVA、IOP和UP无差异。第1组的平均基线和术后SM分别为2063和1910个细胞/mm²,内皮细胞损失(ECL)为153.89±189。第2组的平均基线和术后SM分别为2153和1948个细胞/mm²,ECL为205±200。两组间差异无统计学意义(p = 0.105)。

结论

第2组的ECL似乎更高,但差异不显著。两组的最终临床结果相似。在某些特定情况下,不使用OVD的PE手术可能更可取,以降低经济状况较差地区的手术成本,并预防这些器械的副作用。

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