Inacio Maria C S, Graves Stephen E, Pratt Nicole L, Roughead Elizabeth E, Nemes Szilard
School of Pharmacy and Medical Sciences, Medicine and Device Surveillance Centre of Research Excellence, Sansom Institute, University of South Australia, GPO Box 2471, Adelaide, 5001, SA, Australia.
Australian Orthopaedic Association National Total Joint Replacement Registry, South Australian Health and Medical Research Institute, Adelaide, Australia.
Clin Orthop Relat Res. 2017 Aug;475(8):2130-2137. doi: 10.1007/s11999-017-5377-7. Epub 2017 May 9.
The incidence of joint arthroplasty is increasing worldwide. International estimates of future demand for joint arthroplasty have used models that propose either an exponential future increase, despite obvious system constraints, or static increases, which do not account for past trends. Country-specific projection estimates that address limitations of past projections are necessary. In Australia, a high-income country with the 7th highest incidence of TKA and 15th highest incidence of THA of the Organization for Economic Cooperation and Development (OECD) countries, the volume of TKAs and THAs increased 198% between 1994 and 2014.
QUESTIONS/PURPOSE: To determine the projected incidence and volume of primary TKAs and THAs from 2014 to 2046 in the Australian population older than 40 years.
Australian State and Territory Health Department data were used to identify TKAs and THAs performed between 1994 and 1995 and 2013 and 2014. The Australian Bureau of Statistics was the source of the population estimates for the same periods and population-projected estimates until 2046. The incidence rate (IR), 95% CI, and prediction interval (PI) of TKAs and THAs per 100,000 Australian citizens older than 40 years were calculated. Future IRs were estimated using a logistic model, and volume was calculated from projected IR and population. The logistic growth model assumes the existence of an upper limit of the TKA and THA incidences and a growth rate directly related to this incidence. At the beginning, when the observed incidence is much lower than the asymptote, the increase is exponential, but it decreases as it approaches the upper limit.
A 66% increase in the IR of primary THAs between 2013 and 2046 is projected for Australia (2013: IR = 307 per 100,000, [95% CI, 262-329 per 100,000] compared with 2046: IR= 510 per 100,000, [95% PI, 98-567 per 100,000]), which translates to a 219% increase in the volume during this period. For TKAs the IR is expected to increase by 26% by 2046 (IR = 575 per 100,000; 95% PI, 402-717 per 100,000) compared with 2013 (IR = 437 per 100,000; 95% CI, 397-479 per 100,000) and the volume to increase by 142%.
A large increase in the volume of arthroplasties is expected using a conservative projection model that accounts for past surgical trends and future population changes in Australia. These findings have international implications, as they show that using country- specific, conservative projection approaches, a substantial increase in the number of these procedures is expected. This increase in joint arthroplasty volume will require appropriate workforce planning, resource allocation, and budget planning so that demand can be met.
Level II, economic and decision analysis.
全球关节置换术的发病率正在上升。国际上对关节置换术未来需求的估计使用的模型,要么提出未来呈指数增长,尽管存在明显的系统限制;要么提出静态增长,而这并未考虑过去的趋势。有必要进行针对特定国家的预测估计,以解决过去预测的局限性。在澳大利亚,作为一个高收入国家,在经济合作与发展组织(经合组织)国家中全膝关节置换术(TKA)发病率排名第七,全髋关节置换术(THA)发病率排名第十五,1994年至2014年间,TKA和THA的手术量增长了198%。
问题/目的:确定2014年至2046年澳大利亚40岁以上人群中初次TKA和THA的预计发病率和手术量。
利用澳大利亚州和领地卫生部的数据,确定1994年至1995年以及2013年至2014年期间实施的TKA和THA手术。澳大利亚统计局是同期人口估计数以及直至2046年的人口预测估计数的来源。计算每10万名40岁以上澳大利亚公民的TKA和THA发病率(IR)、95%置信区间(CI)和预测区间(PI)。使用逻辑模型估计未来发病率,并根据预测的发病率和人口计算手术量。逻辑增长模型假设TKA和THA发病率存在上限,且增长率与该发病率直接相关。一开始,当观察到的发病率远低于渐近线时,增长是指数式的,但随着接近上限,增长会下降。
预计2013年至2046年澳大利亚初次THA的发病率将增加66%(2013年:IR = 每10万人307例,[95% CI,每10万人262 - 329例],相比之下2046年:IR = 每10万人510例,[95% PI,每10万人98 - 567例]),这意味着在此期间手术量将增加219%。对于TKA,预计到2046年发病率将增加26%(IR = 每10万人575例;95% PI,每10万人402 - 717例),相比2013年(IR = 每10万人437例;95% CI,每10万人397 - 479例),手术量将增加142%。
使用考虑了澳大利亚过去手术趋势和未来人口变化的保守预测模型,预计关节置换术的手术量将大幅增加。这些发现具有国际意义,因为它们表明,采用针对特定国家的保守预测方法,预计这些手术的数量将大幅增加。关节置换术手术量的这种增加将需要进行适当的劳动力规划、资源分配和预算规划,以便能够满足需求。
二级,经济和决策分析。