Allen Michelle J, Brain David, Crawford Ross, Senanayake Sameera, Harris Ian A, Elliott Lana M, Hinchcliff Reece, McCreanor Victoria, McPhail Steven M
Australian Centre for Health Services Innovation and Centre for Healthcare Transformation, School of Public Health and Social Work, Queensland University of Technology, Brisbane, Queensland, Australia
Australian Centre for Health Services Innovation and Centre for Healthcare Transformation, School of Public Health and Social Work, Queensland University of Technology, Brisbane, Queensland, Australia.
BMJ Open. 2025 Mar 7;15(3):e088986. doi: 10.1136/bmjopen-2024-088986.
There is increasing demand for knee and hip arthroplasty with considerable health system cost implications. Despite the high surgical costs relating to the prosthesis used, little is known about which factors are most influential in prosthesis choice, nor is it clear what level of variation may be warranted for clinical reasons.
This study had dual objectives: (1) identify factors influencing prosthesis selection for total hip arthroplasty (THA) and total knee arthroplasty (TKA) and (2) develop a working definition for unwarranted variation in THA and TKA implant selection.
A three-stage prospective study: (1) develop and pilot a questionnaire with input from orthopaedic surgeons; (2) a cross-sectional survey with orthopaedic surgeons across Australia and (3) an expert panel to finalise the working definition of unwarranted variation.
Study activities were conducted both virtually and in person, primarily with hospital-based orthopaedic surgeons and orthopaedic registrars across Australia, but also included health economists and health administrators in the expert panel stage.
Revision rates, familiarity with an implant and implant quality were prioritised when choosing a prosthesis, while other factors, including cost, were reported to have limited influence. Technological advancement and revision rates were influential for past changes in prostheses, and strong clinical evidence is expected to precede future changes. The consensus was reached on a working definition of unwarranted variation that focused on implants with revision rates of 20% or higher compared with published benchmarks. The use of multiple cost thresholds was recommended for defining narrow and broad definitions of unwarranted variation.
Study findings provide valuable insights into the decision-making process for prosthesis selection, as well as what surgeons believe might constitute unwarranted variation. This information can advance our understanding of the magnitude and impact of unwarranted variation in prosthesis selection, as well as inform strategies to address it.
膝关节和髋关节置换术的需求日益增加,这对卫生系统成本产生了重大影响。尽管与所使用的假体相关的手术成本很高,但对于哪些因素在假体选择中最具影响力知之甚少,也不清楚出于临床原因可能需要何种程度的差异。
本研究有两个目标:(1)确定影响全髋关节置换术(THA)和全膝关节置换术(TKA)假体选择的因素;(2)为THA和TKA植入物选择中不必要的差异制定一个可行的定义。
一项三阶段前瞻性研究:(1)在骨科医生的参与下制定并试用一份问卷;(2)对澳大利亚各地的骨科医生进行横断面调查;(3)成立一个专家小组来确定不必要差异的可行定义。
研究活动通过线上和线下方式进行,主要参与者是澳大利亚各地医院的骨科医生和骨科住院医生,专家小组阶段还包括卫生经济学家和卫生管理人员。
选择假体时,翻修率、对植入物的熟悉程度和植入物质量是首要考虑因素,而包括成本在内的其他因素影响有限。技术进步和翻修率对过去的假体变化有影响,预计未来的变化将有强有力的临床证据支持。就不必要差异的可行定义达成了共识,该定义侧重于翻修率比已发表基准高20%或更高的植入物。建议使用多个成本阈值来定义不必要差异的狭义和广义定义。
研究结果为假体选择的决策过程提供了有价值的见解,以及外科医生认为可能构成不必要差异的因素。这些信息可以增进我们对假体选择中不必要差异的程度和影响的理解,并为解决该问题的策略提供参考。