史蒂文斯-约翰逊综合征/中毒性表皮坏死松解症及生物制剂治疗：一例报告
Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis and Treatment With a Biologic: A Case Report.
作者信息
Chong Ian, Chao Alice
机构信息
Attending Physician in Emergency Medicine at the Zion Medical Center in San Diego, CA.
Attending Physician in Emergency Medicine at the Santa Clara Medical Center in CA.
出版信息
Perm J. 2017;21:16-060. doi: 10.7812/TPP/16-060.
Abstract
INTRODUCTION
One of the most dangerous dermatologic emergencies is Stevens-Johnson Syndrome (SJS)/toxic epidermal necrolysis (TEN). Although a rare disease, it can often lead to significant mortality.
CASE PRESENTATION
In this case report, we present a 77-year-old man who developed a sloughing rash that was secondary to a nonsteroidal anti-inflammatory drug. In addition to the recommended supportive care, the patient was treated with etanercept, a new, less commonly used intervention.
DISCUSSION
We provide a brief review of SJS/TEN. Nonsteroidal anti-inflammatory drugs are a rare cause of SJS/TEN, and additionally, the use of biologics is a novel treatment modality for SJS/TEN.
摘要
引言
史蒂文斯-约翰逊综合征（SJS）/中毒性表皮坏死松解症（TEN）是最危险的皮肤科急症之一。尽管是一种罕见疾病，但它常常会导致较高的死亡率。
病例报告
在本病例报告中，我们介绍了一名77岁男性，他因非甾体抗炎药引发了脱皮性皮疹。除了推荐的支持性治疗外，该患者还接受了依那西普治疗，这是一种新的、较少使用的干预措施。
讨论
我们简要回顾了SJS/TEN。非甾体抗炎药是SJS/TEN的罕见病因，此外，生物制剂的使用是SJS/TEN的一种新型治疗方式。
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