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依那西普治疗儿童史蒂文斯-约翰逊综合征/中毒性表皮坏死松解症。

Pediatric Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Halted by Etanercept.

机构信息

1 Children's Hospital of Eastern Ontario, Ottawa, ON, Canada.

2 University of Ottawa, Ottawa, ON, Canada.

出版信息

J Cutan Med Surg. 2018 Sep/Oct;22(5):514-515. doi: 10.1177/1203475418758989. Epub 2018 Feb 9.

Abstract

We report a case of an 11-year-old female with Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) overlap, most likely triggered by sulfamethoxazole-trimethoprim, who was treated with the combination of methylprednisolone, cyclosporine, and etanercept. Her condition stabilized and her skin involvement did not progress after the addition of etanercept. To our knowledge, this is the first report of etanercept for pediatric SJS/TEN.

摘要

我们报告了一例 11 岁女性史蒂文斯-约翰逊综合征(SJS)/中毒性表皮坏死松解症(TEN)重叠病例,很可能由磺胺甲噁唑-甲氧苄啶引发,该患者接受了甲泼尼龙、环孢素和依那西普联合治疗。在加用依那西普后,她的病情稳定,皮肤受累没有进展。据我们所知,这是首例依那西普治疗儿科 SJS/TEN 的报告。

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