Hessami Arani S, Kerachian M A
Department of Nutrition, Faculty of Medicine, and.
Medical Genetics Research Center, Mashhad University of Medical Sciences.
Curr Oncol. 2017 Apr;24(2):e131-e137. doi: 10.3747/co.23.3226. Epub 2017 Apr 27.
Colorectal cancer (crc) is one of the most prevalent cancers in the world. Although the incidence of crc is currently very low in the older Iranian population compared with Western populations, young Iranians show a rising trend of crc-that is, the age-adjusted rate is close in the young Iranian population compared with the U.S. population, and the rate in older Iranians is much lower.
To assess a putative relationship between diet and a rising rate of crc in younger Iranians, a combined text word and mesh heading search strategy identified relevant studies through Google Scholar and medline.
A critical look at diet among Iranians shows major issues that might be raising the risk for crc. There are also scenarios other than diet for the rise, such as the young age structure of the country. However, the actual scenario is more complex.
In Iran, crc is one of the most common incident cancers and a common cause of cancer death. Primary and secondary prevention-with attention to a healthy lifestyle, physical activity, and screening-should be enhanced in the general population.
结直肠癌（CRC）是世界上最常见的癌症之一。尽管与西方人群相比，目前伊朗老年人群中CRC的发病率非常低，但年轻伊朗人的CRC发病率呈上升趋势——也就是说，伊朗年轻人的年龄调整发病率与美国人群相近，而伊朗老年人的发病率则低得多。
为了评估饮食与伊朗年轻人中CRC发病率上升之间的假定关系，采用文本词和主题词组合搜索策略，通过谷歌学术和医学期刊数据库（Medline）确定相关研究。
对伊朗人的饮食进行批判性审视会发现一些可能增加CRC风险的主要问题。除了饮食之外，还有其他导致发病率上升的因素，比如该国年轻的年龄结构。然而，实际情况更为复杂。
在伊朗，CRC是最常见的新发癌症之一，也是癌症死亡的常见原因。应在普通人群中加强一级和二级预防，同时关注健康的生活方式、体育活动和筛查。
